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data from the International Head and Neck Cancer Epidemiology (INHANCE) consortium to compare cigarette smoking and alcohol consumption risk factors for head and neck cancer between less developed and more developed countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>The location of each study was categorized as either a less developed or more developed country. We compared the risk of overall head and neck cancer and cancer of specific anatomic subsites associated with cigarette smoking and alcohol consumption. Additionally, age and sex distribution between categories was compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The odds ratios for head and neck cancer sites associated with smoking duration differed between less developed and more developed countries. Smoking greater than 20\u00a0years conferred a higher risk for oral cavity and laryngeal cancer in more developed countries, whereas the risk was greater for oropharynx and hypopharynx cancer in less developed countries. Alcohol consumed for more than 20\u00a0years conferred a higher risk for oropharynx, hypopharynx, and larynx cancer in less developed countries. The proportion of cases that were young (&lt;45\u00a0years) or female differed by country type for some HNC subsites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings suggest the degree of industrialization and economic development affects the relationship between smoking and alcohol with head and neck cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14196","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T18:14:08Z","timestamp":1648145648000},"page":"1565-1578","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Risk factors for head and neck cancer in more and less developed countries: Analysis from the INHANCE consortium"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7783-1097","authenticated-orcid":false,"given":"Neerav","family":"Goyal","sequence":"first","affiliation":[{"name":"College of Medicine The Pennsylvania State University  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"Hennessy","sequence":"additional","affiliation":[{"name":"College of Medicine The Pennsylvania State University  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Lehman","sequence":"additional","affiliation":[{"name":"College of Medicine The Pennsylvania State University  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxue","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Medicine The Pennsylvania State University  Hershey Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Agudo","sequence":"additional","affiliation":[{"name":"Institut Catala Oncologia  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Ahrens","sequence":"additional","affiliation":[{"name":"Faculty of Mathematics and Computer Science Institute of Statistics Leibniz Institute for Prevention Research and Epidemiology, BIPS, and University of Bremen  Bremen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Boccia","sequence":"additional","affiliation":[{"name":"Sezione di Igiene Dipartimento Universitario di Scienze della Vita e Sanit\u00e0 Pubblica Universit\u00e0 Cattolica del Sacro Cuore  Roma Italia"},{"name":"Department of Woman and Child Health and Public Health \u2010 Public Health Area Fondazione Policlinico Universitario A. 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