{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:34:12Z","timestamp":1791952452524,"version":"4.3.4"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,9]],"date-time":"2022-05-09T00:00:00Z","timestamp":1652054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008133","name":"Universidade de Pernambuco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>to investigate the impact of the severity of microcephaly caused by the Zika virus (MCZ) on tooth eruption and orofacial structures of children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      This case series study developed the research at the Mens Sana Rehabilitation Center, Arcoverde, Brazil. The study included 27 children diagnosed with MCZ. We performed the data collection in June 2018 through a questionnaire answered by the legal guardians, followed by a clinical examination of the children. The data were analyzed by the Mann\u2013Whitney and Fisher's exact tests (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The final sample was composed of 20 children. Of these, 13 (35.0%) had severe microcephaly, 5 (30.0%) had altered sequence of tooth eruption, 10 (50.0%) had delayed eruption, and the mean number of decayed teeth was 2.3. The most identified orofacial changes were teeth grinding habit (65.0%), difficult chewing (50.0%), and non\u2010nutritive sucking (50.0%). The Mann\u2013Whitney test showed that the severity of microcephaly did not affect tooth eruption (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.581). The Fisher's exact test showed that the severity of microcephaly was not associated with orofacial changes (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&gt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The severity of MCZ does not seem to influence changes in deciduous tooth eruption and the presence of orofacial anomalies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14227","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T04:27:29Z","timestamp":1651206449000},"page":"2277-2282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Might Zika virus\u2010associated microcephaly's severity impact deciduous tooth eruption and orofacial structures?"],"prefix":"10.1111","volume":"29","author":[{"given":"Fernando Fl\u00e1vio Souza","family":"Vaz","sequence":"first","affiliation":[{"name":"Multiprofessional Residency Program in Public Health of the Health Secretary of Recife  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano Referino","family":"da Silva Sobrinho","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Socioenvironmental Development Universidade de Pernambuco  Garanhuns Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Regina Ribeiro Santos","family":"Athayde","sequence":"additional","affiliation":[{"name":"School of Dentistry Universidade de Pernambuco  Arcoverde Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"de Vasconcelos Carvalho","sequence":"additional","affiliation":[{"name":"School of Dentistry Universidade de Pernambuco  Arcoverde Pernambuco Brazil"},{"name":"Graduate Program in Dentistry Universidade de Pernambuco  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9119-8435","authenticated-orcid":false,"given":"Pedro Henrique","family":"Sette\u2010de\u2010Souza","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Socioenvironmental Development Universidade de Pernambuco  Garanhuns Pernambuco Brazil"},{"name":"School of Dentistry Universidade de Pernambuco  Arcoverde Pernambuco Brazil"},{"name":"Graduate Program in Dentistry Universidade de Pernambuco  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stef\u00e2nia Jeronimo","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Graduate Program in Health and Socioenvironmental Development Universidade de Pernambuco  Garanhuns Pernambuco Brazil"},{"name":"School of Dentistry Universidade de Pernambuco  Arcoverde Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4034\/PBOCI.2018.181.16"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807\u20103107bor\u20102021.vol35.0043"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedp.2018.08.009"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.23865"},{"key":"e_1_2_6_6_1","unstructured":"Brasil. 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