{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:29:01Z","timestamp":1790368141820,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: Worldwide millions peoples consume AN who are at risk of OSMF. Prevalence of OSMF is reported between 0.03% and 30% irrespective of AN habit. Further, these estimates are based on sample population comprised of OSMF patients or general population rather AN chewers (ANC). Therefore, available evidence does not reflect the true prevalence of OSMF among ANC. Method: The studies providing the prevalence of OSMF in ANC were identified in PubMed, Scopus, and Web of Science. Pooled prevalence and quality assessment using New\u2010Ottawa Scale were performed. Results: Fifteen studies reported the prevalence of OSMF (929) in ANC (53,213). Most studies were from China (six studies) and India (four studies) correlating with regions having high ANC. The pooled prevalence of OSMF in ANC was 5% (0.05 [95% CI, 0.03, 0.08]). All studies' quality was satisfactory; however, the OSMF diagnosis method, age, gender, and habits need further scrutiny. Conclusion: Available evidence suggested a low prevalence of OSMF in ANC, although further large\u2010scale studies are recommended to validate this finding. Understanding the prevalence and distribution patterns of OSMF might aid intervention healthcare programs and contribute to the reduction of the oral cancer burden related to OSMF.<\/jats:p>","DOI":"10.1111\/odi.14235","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T12:50:16Z","timestamp":1651582216000},"page":"1920-1926","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Prevalence of oral submucous fibrosis among areca nut chewers: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9233-8292","authenticated-orcid":false,"given":"Monal","family":"Yuwanati","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences Saveetha University  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9408-3158","authenticated-orcid":false,"given":"Ramya","family":"Ramadoss","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences Saveetha University  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0392-7720","authenticated-orcid":false,"given":"Yasusei","family":"Kudo","sequence":"additional","affiliation":[{"name":"Department of Oral Bioscience Graduate School of Biomedical Sciences Tokushima University  Tokushima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratibha","family":"Ramani","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences Saveetha University  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mullainathan","family":"Senthil Murugan","sequence":"additional","affiliation":[{"name":"Oral Oncology Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences Saveetha University  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2010.01.017"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2008.10400646"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.12"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2005.00332.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1996.tb03136.x"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826084.2019.1657149"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1980.tb01302.x"},{"key":"e_1_2_12_9_1","first-page":"113","article-title":"Oral submucous fibrosis in India: A new epidemic?","volume":"11","author":"Gupta P. C.","year":"1998","journal-title":"National Medical Journal of India"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172196"},{"key":"e_1_2_12_11_1","first-page":"299","article-title":"A clinical study of oral submucous fibrosis","volume":"24","author":"Jian X. C.","year":"1989","journal-title":"Chinese Journal of Stomatology"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13727"},{"key":"e_1_2_12_13_1","first-page":"81","article-title":"A study of oral submucous fibrosis","volume":"4","author":"Liu S.","year":"1988","journal-title":"Chinese Journal of Stomatology"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(17)30460-6"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12726"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2020.08.004"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1990.tb00805.x"},{"key":"e_1_2_12_18_1","first-page":"656","article-title":"Areca (betel) nut chewing habit among high\u2010school children in the Commonwealth of the Northern Mariana Islands (Micronesia)","volume":"83","author":"Oakley E.","year":"2005","journal-title":"Bulletin of the World Health Organization"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472\u20106831\u201014\u2010151"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1968.76"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0904-2512.2004.00116.x"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463\u2010020\u20100399\u20107"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2013.02.025"},{"key":"e_1_2_12_25_1","first-page":"568","article-title":"Betel\u2010nut chewing and submucous fibrosis in Durban","volume":"74","author":"Seedat H. A.","year":"1988","journal-title":"South African Medical Journal"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10001-1288"},{"key":"e_1_2_12_27_1","first-page":"61","article-title":"A contemporary narrative review to guide molecular epidemiology of oral submucous fibrosis","volume":"12","author":"Singh A. G.","year":"2021","journal-title":"International Journal of Molecular Epidemiology and Genetics"},{"key":"e_1_2_12_28_1","article-title":"Areca nut consumption with and without tobacco among the adult population: A nationally representative study from India","volume":"11","author":"Singh P. K.","year":"2021","journal-title":"British Medical Journal Open"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1997.tb00918.x"},{"key":"e_1_2_12_30_1","first-page":"130","article-title":"A study of 335 cases of oral submucous fibrosis","volume":"11","author":"Tang J.","year":"1993","journal-title":"West China Journal of Stomatology"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2020.1860272"},{"key":"e_1_2_12_32_1","volume-title":"The Newcastle\u2010Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta\u2010analyses","author":"Wells G.","year":"2000"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2017.01.012"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2001.300404.x"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-8-199"},{"key":"e_1_2_12_36_1","first-page":"391","article-title":"Epidemiological investigation of chewing fresh or dried betel nut and oral mucosal disease","volume":"34","author":"Yongxiu D.","year":"2016","journal-title":"Hua Xi Kou Qiang Yi Xue Za Zhi"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp\u2010journals\u201010024\u20103101"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2012.01166.x"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.14235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/odi.14235","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.14235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T17:25:44Z","timestamp":1692465944000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.14235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,20]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/odi.14235"],"URL":"https:\/\/doi.org\/10.1111\/odi.14235","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/ODI.14235\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v1\/review4","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v3\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14235\/v3\/decision1","asserted-by":"object"}]},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,20]]},"assertion":[{"value":"2021-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}