{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T13:51:04Z","timestamp":1792245064054,"version":"4.4.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,2,19]],"date-time":"2023-02-19T00:00:00Z","timestamp":1676764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003758","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico do Maranh\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate orofacial traits and general factors related to oral health\u2010related quality of life in acromegaly patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study with 34 acromegaly patients was conducted. The OHIP\u201014 questionnaire was used to assess oral health\u2010related quality of life scores. To assess orofacial and occlusion morphology, an oral evaluation was performed. Correlation measures, multiple linear regression and a structural equation model (SEM) were used in the statistical analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The presence of arthrosis (SC\u00a0=\u00a00.467, SE\u00a0=\u00a00.155,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003) and smoking history (SC\u00a0=\u00a00.459, SE\u00a0=\u00a00.206,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.026) were associated with a negative impact on oral health\u2010related quality of life. Mandibular protrusion was related to physical pain (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a02.74,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.029). Anterior open bite (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a04.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.004) and anterior crossbite (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a02.61,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.026) were related to psychological disability. Diastema was related to social disability (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a03.42,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.037) and handicap (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a02.74,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.044).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings suggest that smoking, arthrosis and orofacial alterations (mandibular protrusion, open bite, crossbite and diastema) have a negative impact on oral health\u2010related quality of life in acromegaly patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14511","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:54:58Z","timestamp":1674089698000},"page":"1652-1659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Orofacial traits related to oral health\u2010related quality of life in Brazilian acromegaly patients"],"prefix":"10.1111","volume":"30","author":[{"given":"Renata C.","family":"Campelo","sequence":"first","affiliation":[{"name":"School of Dentistry Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5822-0848","authenticated-orcid":false,"given":"Maria L. M.","family":"da Silva","sequence":"additional","affiliation":[{"name":"School of Dentistry Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3373-4372","authenticated-orcid":false,"given":"Gilvan C.","family":"Nascimento","sequence":"additional","affiliation":[{"name":"Service of Endocrinology Presidente Dutra University Hospital  S\u00e3o Lu\u00eds Brazil"},{"name":"Research Group in Clinical and Molecular Endocrinology and Metabology (ENDOCLIM)  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6097-8145","authenticated-orcid":false,"given":"Rossana S. S.","family":"Azulay","sequence":"additional","affiliation":[{"name":"Service of Endocrinology Presidente Dutra University Hospital  S\u00e3o Lu\u00eds Brazil"},{"name":"Research Group in Clinical and Molecular Endocrinology and Metabology (ENDOCLIM)  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2498-3289","authenticated-orcid":false,"given":"Viviane C. C.","family":"Rocha","sequence":"additional","affiliation":[{"name":"Service of Endocrinology Presidente Dutra University Hospital  S\u00e3o Lu\u00eds Brazil"},{"name":"Research Group in Clinical and Molecular Endocrinology and Metabology (ENDOCLIM)  S\u00e3o Lu\u00eds Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6531-8122","authenticated-orcid":false,"given":"Sabrina S. 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