{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:48Z","timestamp":1772160828585,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T00:00:00Z","timestamp":1676937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004912","name":"Sichuan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To explore the prognostic effects of previous cancer history on patients with major salivary gland cancer (SGC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>SGC patients with (sec\u2010SGC) and without (one\u2010SGC) a previous cancer from the SEER database were identified. Cox proportional hazards regression (CoxPH) models were used to compare the prognosis between sec\u2010SGC and one\u2010SGC patients. Subgroup analyses for sec\u2010SGC patients by gender, previous cancer types, previous cancer histology, and cancer diagnosis interval (CDI) were performed. Two CoxPH models were constructed to distinguish sec\u2010SGC patients with different prognostic risks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      9098 SGC patients were enrolled. Overall, sec\u2010SGC patients (adjusted HR [aHR]\u00a0=\u00a01.26,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), especially those with a CDI\u2009\u2264\u20095\u2009years (aHR\u00a0=\u00a01.47,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), had worse overall survival (OS) than one\u2010SGC patients. In subgroup analysis, only sec\u2010SGC patients with a previous head and neck cancer who were female (aHR\u00a0=\u00a02.38,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.005), with a CDI\u2009\u2264\u20095\u2009years (aHR\u00a0=\u00a01.65,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.007) or with a previous squamous cell carcinoma (aHR\u00a0=\u00a06.52,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) had worse OS. Our models successfully differentiated all sec\u2010SGC patients into high\u2010, intermediate\u2010 and low\u2010risk groups with different prognosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Sec\u2010SGC patients with different previous cancer types, gender, CDI and previous cancer histology had varied prognosis. The models we constructed could help differentiate the prognosis of sec\u2010SGC patients with different risks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14530","type":"journal-article","created":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T02:53:44Z","timestamp":1675652024000},"page":"492-503","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic effects of previous cancer history on patients with major salivary gland cancer"],"prefix":"10.1111","volume":"30","author":[{"given":"Junhong","family":"Li","sequence":"first","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology, West China Hospital Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yufang","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Oto\u2010Rhino\u2010Laryngology, West China Hospital Sichuan University Chengdu 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