{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:50Z","timestamp":1772160830900,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T00:00:00Z","timestamp":1687219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01\u2010DE026924"],"award-info":[{"award-number":["R01\u2010DE026924"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>People living with HIV (PLWH) have been shown to have lower bone density at the spine, hip, and radius. However, whether a similar bone phenotype is seen in craniofacial bones is not known. The goal of this study was to evaluate the bone microarchitecture of the mandibular condyle in PLWH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We recruited 212 participants, which included 88 HIV\u2010negative participants and 124 PLWH on combination antiretroviral therapy with virological suppression from a single academic center. Each participant filled out a validated temporomandibular disorder (TMD) pain screening questionnaire and had cone beam computed tomography (CBCT) of their mandibular condyles. Qualitative radiographic evidence of temporomandibular joint disorders\u2010osteoarthritis (TMJD\u2010OA) assessment and quantitative microarchitecture analysis of their mandibular condylar bones were conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There was no statistically significant difference in either self\u2010reported TMD or in radiographic evidence of TMJD\u2010OA in PLWH compared with HIV\u2010negative controls. Linear regression analysis revealed that positive HIV status remained significantly associated with increased trabecular thickness, decreased cortical porosity, and increased cortical bone volume fraction after adjusting for race, diabetes, sex, and age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PLWH have increased mandibular condylar trabecular bone thickness and cortical bone volume fraction compared with HIV\u2010negative controls.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14651","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T07:40:02Z","timestamp":1687246802000},"page":"2355-2361","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the mandibular condylar bone microarchitecture in people living with\n                    <scp>HIV<\/scp>"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5743-9231","authenticated-orcid":false,"given":"Sunil","family":"Wadhwa","sequence":"first","affiliation":[{"name":"Division of Orthodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Levit","sequence":"additional","affiliation":[{"name":"Division of Orthodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2774-3560","authenticated-orcid":false,"given":"Satoko","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin Jung","family":"Hsieh","sequence":"additional","affiliation":[{"name":"Division of Orthodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7481-0418","authenticated-orcid":false,"given":"Karolina","family":"Kister","sequence":"additional","affiliation":[{"name":"Division of Orthodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2305-737X","authenticated-orcid":false,"given":"Cleber","family":"Silva","sequence":"additional","affiliation":[{"name":"Division of Oral and Maxillofacial Radiology Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayesh","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Columbia University College of Physicians and Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2828-0281","authenticated-orcid":false,"given":"Anyelina","family":"Cantos","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Columbia University College of Physicians and Surgeons  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8961-6968","authenticated-orcid":false,"given":"Bruno","family":"Bohn","sequence":"additional","affiliation":[{"name":"School of Public Health University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3429-0379","authenticated-orcid":false,"given":"Ryan T.","family":"Demmer","sequence":"additional","affiliation":[{"name":"School of Public Health University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9346-9056","authenticated-orcid":false,"given":"Michael T.","family":"Yin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Columbia University College of Physicians and Surgeons  New York New York 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