{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:49:23Z","timestamp":1788544163401,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T00:00:00Z","timestamp":1687219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100016714","name":"University of Sharjah","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016714","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Thy\u20101 (CD90) is a glycosylphosphatidyl\u2010anchored protein belonging to the immunoglobulin family and is known to control mesenchymal stromal cells differentiation into osteoblasts or adipocytes. The study aimed to investigate the salivary levels of Thy\u20101 in health, periodontitis, obesity, and any potential association.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Seventy\u2010one participants were divided into four groups: healthy (H), subjects with periodontitis (P), obese individuals (O), and obese individuals having periodontitis (PO). Unstimulated whole saliva was collected from participants who were evaluated for periodontal parameters. The levels of Thy\u20101 were measured with a commercially available ELISA kit. The data were statistically analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant difference in salivary Thy\u20101 levels among different groups was observed. Periodontitis patients had the maximum, and obese individuals had the minimum Thy\u20101 levels. Significant differences between H and P, H and PO, P and O, and O and PO were observed. Overall correlations between Thy\u20101 and periodontal parameters and a positive correlation with pocket depth in group PO were noted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Thy\u20101 could be detected in the saliva of all study participants. It is implied that a local inflammatory condition like periodontitis elevates the salivary levels of Thy\u20101 with, and without obesity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.14652","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T11:39:37Z","timestamp":1687261177000},"page":"2670-2677","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of salivary Thy\u20101 in health, periodontitis, and obesity"],"prefix":"10.1111","volume":"30","author":[{"given":"Hawra\u2019a Wisam","family":"Al\u2010Ameri","sequence":"first","affiliation":[{"name":"Department of Preventive and Restorative Dentistry, College of Dental Medicine University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunaina","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Preventive and Restorative Dentistry, College of Dental Medicine University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betul","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Preventive and Restorative Dentistry, College of Dental Medicine University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aghila Rani Koippallil","family":"Gopalakrishnan","sequence":"additional","affiliation":[{"name":"Sharjah Institute for Medical Research University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmaa Anwer","family":"Ismail","sequence":"additional","affiliation":[{"name":"Sharjah Institute for Medical Research University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2062-5791","authenticated-orcid":false,"given":"Anirudh B.","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Preventive and Restorative Dentistry, College of Dental Medicine University of Sharjah  Sharjah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12947"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010013\u20101056\u20106"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.02.012"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41415\u2010019\u20100611\u20101"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2012.178"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802479"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2012.0637"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.b.20461"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010food\u2010030212\u2010182700"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12935"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17\u20100719"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2020.151636"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2016.09.002"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090630"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.3.260"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102458\u20109\u201088"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510373765"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12326"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.140589"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.90"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14409"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.05.022"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12634"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12104"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515609882"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2008.0353"},{"key":"e_1_2_11_28_1","volume-title":"Carranza's clinical periodontology","author":"Newman M. 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