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Although oral microbiota\u2013host interactions are closely associated with the development of OSCC, the interrelationship between fungi and OSCC is poorly understood compared to that between bacteria and viruses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We accumulated knowledge of the evidence, pathogenic factors, and possible multiple mechanisms by which\n                      <jats:italic>C. albicans<\/jats:italic>\n                      promotes malignant transformation of OSCC, focusing on the induction of epithelial damage, production of carcinogens, and regulation of the tumor microenvironment. In addition, we highlight the latest treatment strategies for\n                      <jats:italic>Candida<\/jats:italic>\n                      infection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This review provides a new perspective on the interrelationship between\n                      <jats:italic>C. albicans<\/jats:italic>\n                      and OSCC and contributes to the establishment of a systematic and reliable clinical treatment system for OSCC patients with\n                      <jats:italic>C. albicans<\/jats:italic>\n                      infection.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14700","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T08:44:41Z","timestamp":1690965881000},"page":"1873-1886","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The evil companion of\n                    <scp>OSCC<\/scp>\n                    :\n                    <i>Candida albicans<\/i>"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3751-2800","authenticated-orcid":false,"given":"Zhixin","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology Sichuan University  Chengdu Sichuan P. 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