{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T04:27:10Z","timestamp":1792297630970,"version":"4.4.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100023652","name":"Sveu\u010dili\u0161te u Rijeci","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023652","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to compare the healing of periapical bone between type II diabetes patients and healthy patients after root canal treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>This study included 26 diabetic patients and the control group with healthy patients matching the diabetic group in age and sex. The study included only teeth with satisfactory coronal restoration. The periapical index system was used to evaluate the periapical status of treated teeth at follow\u2010ups after 6 and 12\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Analysis of the results revealed a significantly higher healing rate in the control group compared to the diabetic group only at the 6\u2010month follow\u2010up (66.6 vs. 33.3%; \u03a7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20094.857;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0275). Analysis of the full\u2010scale PAI index disclosed significantly higher PAI values in the diabetic subjects at 6\u2010 and 12\u2010month follow\u2010up. The regression analysis showed that the risk of apical periodontitis persistence increased significantly with female gender (OR\u2009=\u20093.92; 95% CI\u2009=\u20091.04\u201314.79;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.043), diabetes mellitus (OR\u2009=\u20094.27; 95% CI: 1.18\u201315.50;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027) and higher household income (OR\u2009=\u20095.39; 95% CI\u2009=\u20091.33\u201321.89;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Root canal treatment remains an effective means of conservative treatment in diabetic patients. While the healing is not compromised, regular follow\u2010ups are necessary to monitor the healing process.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14772","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T01:54:16Z","timestamp":1697507656000},"page":"3422-3430","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Healing of apical periodontitis in type II diabetes mellitus patients: A prospective study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9900-8621","authenticated-orcid":false,"given":"Ema","family":"Paljevi\u0107","sequence":"first","affiliation":[{"name":"Department of Endodontics and Restorative Dentistry, Faculty of Dental Medicine University of Rijeka  Rijeka 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