{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:19:53Z","timestamp":1789233593051,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,9]]},"abstract":"Abstract<\/jats:title>\n \n Objectives<\/jats:title>\n \n We assessed the radiation dosages (\n D<\/jats:italic>\n mean<\/jats:sub>\n ) on implant regions to identify the threshold for implant loss in patients with an intraoral malignancy treated with dental implants to support a mandibular denture during ablative surgery before volumetric\u2010modulated arc therapy (VMAT).\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n Data was collected prospectively from 28 patients treated surgically for an intraoral malignancy, followed by postoperative radiotherapy (VMAT) and analyzed retrospectively. Patients received 2 implants in the native mandible during ablative surgery. Implant\u2010specific\n D<\/jats:italic>\n mean<\/jats:sub>\n values were retrieved from the patients' files. Radiographic bone loss was measured 1\u2009year after implant placement and during the last follow\u2010up appointment. Implant survival was analyzed with the Kaplan\u2013Meier method. Univariate logistic regression and Cox\u2010regression analyses were performed to investigate the effect of increasing implant\u2010specific radiation dosages on implant loss.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Five out of 56 placed implants were lost during follow\u2010up (median 36.0\u2009months, IQR 39.0). Radiographically, peri\u2010implant bone loss occurred in implants with a\n D<\/jats:italic>\n mean<\/jats:sub>\n \u2009>\u200940\u2009Gy. Implant loss occurred only in implants with a\n D<\/jats:italic>\n mean<\/jats:sub>\n \u2009>\u200950\u2009Gy.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n An implant\u2010specific\n D<\/jats:italic>\n mean<\/jats:sub>\n higher than 50\u2009Gy is related to more peri\u2010implant bone loss and, eventually, implant loss.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/odi.14813","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T16:46:43Z","timestamp":1700585203000},"page":"3866-3872","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Site\u2010specific radiation dosage and implant survival in oral cancer patients: A cohort study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7612-5350","authenticated-orcid":false,"given":"Jamie M.","family":"Alberga","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2581-4361","authenticated-orcid":false,"given":"Arjan","family":"Vissink","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1862-4757","authenticated-orcid":false,"given":"Anke","family":"Korfage","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastiaan A. H. J.","family":"de Visscher","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max J. H.","family":"Witjes","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes A.","family":"Langendijk","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerry M.","family":"Raghoebar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery University Medical Center Groningen, University of Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-020-05431-y"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13312"},{"issue":"10","key":"e_1_2_10_4_1","article-title":"Dental implants in irradiated versus nonirradiated patients: A meta\u2010analysis","volume":"36","author":"Chrcanovic B.","year":"2014","journal-title":"Head and Neck"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2018.01.012"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2012.07.001"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2010.10.004"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(02)00191-3"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2014.05.013"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.01930.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-022-04549-z"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(87)90136-8"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2012.09.013"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13696"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2016.07.003"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24479"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2003.08.024"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2016.04.025"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgz006"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13329"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25883"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2008.07.007"},{"issue":"10","key":"e_1_2_10_23_1","first-page":"2103","article-title":"Functional benefits of implants placed during ablative surgery: A 5\u2010years prospective study on the prosthodontic rehabilitation of 56 edentulous oral cancer patients","volume":"36","author":"Wetzels J.\u2010W. G. H.","year":"2016","journal-title":"Head and Neck"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13005"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01160.x"},{"issue":"10","key":"e_1_2_10_26_1","first-page":"2229","article-title":"Viability of dental implants in head and neck cancer irradiated patients: A systematic review","volume":"36","author":"Zen Filho E. V.","year":"2016","journal-title":"Head and Neck"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.14813","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:29:46Z","timestamp":1767850186000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.14813"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,20]]},"references-count":25,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1111\/odi.14813"],"URL":"https:\/\/doi.org\/10.1111\/odi.14813","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/ODI.14813\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14813\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14813\/v1\/decision1","asserted-by":"object"}]},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,20]]},"assertion":[{"value":"2023-07-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}