{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:49:38Z","timestamp":1791215378737,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T00:00:00Z","timestamp":1701648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the efficacy of newly introduced ozonated gels compared with conventional chlorhexidine gel in the home management of periodontal patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>30 patients with bilateral periodontal disease (severity I, complexity II) were enrolled (split\u2010mouth study design). After nonsurgical mechanical periodontal debridement, the teeth were randomly divided into two groups: teeth in the Control group were treated with a chlorhexidine\u2010based gel to aid oral hygiene maneuvers for 2\u2009weeks after the first visit, while teeth in the Test group were treated in the same way with ozone\u2010based gels. After the baseline assessment, the follow\u2010up included assessments at 1, 2, and 6\u2009months. The variables evaluated were clinical attachment loss (CAL), probing pocket depth (PPD), bleeding on probing (BoP), plaque control record (PCR), recession (R), and tooth mobility (TM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      For CAL, PPD, BoP, and PCR, significant intragroup differences were found for both groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), in contrast to intergroup differences (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt; 0.05). No significant differences were found for R and TM.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nonsurgical mechanical periodontal debridement with adjunctive use of ozone and chlorhexidine was found to be effective in periodontal treatment. Ozone could be suggested as an alternative to chlorhexidine.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14829","type":"journal-article","created":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T09:34:51Z","timestamp":1701682491000},"page":"3993-4000","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Ozonized gels vs chlorhexidine in non\u2010surgical periodontal treatment: A randomized clinical trial"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2760-0124","authenticated-orcid":false,"given":"Andrea","family":"Scribante","sequence":"first","affiliation":[{"name":"Unit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences University of Pavia  Pavia Italy"},{"name":"Unit of Dental Hygiene, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences 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