{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:48:54Z","timestamp":1747187334320,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to apply diffusion\u2010weighted imaging to the evaluation of cervical lymph nodes affected by medication\u2010related osteonecrosis of the jaw (MRONJ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective study analysed the diffusion\u2010weighted imaging data of 70 patients with or without MRONJ (Stages 0\u20133). The mean apparent diffusion coefficient (ADC) values of the submandibular (level IB) and superior internal jugular (level IIA) nodes in the control and MRONJ groups were calculated, and differences were analysed using the Mann\u2013Whitney test. Moreover, receiver operating characteristic (ROC) curve analysis was performed to evaluate the ability of ADC values to predict lymph nodes that were affected by MRONJ. <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05 was considered statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median [interquartile range] (\u00d710<jats:sup>\u22123<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup>\/s) of level IB was 0.74 [0.7\u20130.81] and 0.93 [0.84\u20131.09] and that of level IIA was 0.79 [0.76\u20130.85] and 0.97 [0.84\u20131.06] in the control and MRONJ groups respectively. ROC analysis revealed that the ADC value had excellent ability to discriminate between the control and MRONJ groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study findings indicate that diffusion\u2010weighted imaging can contribute to differentiation of MRONJ from other cervical lymph node diseases and facilitate early detection of MRONJ.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.14938","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T05:18:55Z","timestamp":1711084735000},"page":"5154-5159","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Visualising cervical lymph nodes in jaw osteonecrosis using diffusion\u2010weighted imaging"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5764-2002","authenticated-orcid":false,"given":"Hirotaka","family":"Muraoka","sequence":"first","affiliation":[{"name":"Department of Radiology Nihon University School of Dentistry at Matsudo 2\u2010870\u20101 Sakaecho\u2010Nishi  Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Kaneda","sequence":"additional","affiliation":[{"name":"Department of Radiology Nihon University School of Dentistry at Matsudo 2\u2010870\u20101 Sakaecho\u2010Nishi  Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Radiology Nihon University School of Dentistry at Matsudo 2\u2010870\u20101 Sakaecho\u2010Nishi  Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Otsuka","sequence":"additional","affiliation":[{"name":"Department of Radiology Nihon University School of Dentistry at Matsudo 2\u2010870\u20101 Sakaecho\u2010Nishi  Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Tokunaga","sequence":"additional","affiliation":[{"name":"Department of Radiology Nihon University School of Dentistry at Matsudo 2\u2010870\u20101 Sakaecho\u2010Nishi  Matsudo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,21]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010005\u20100133\u2010x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2008.12.002"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2007.08.025"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2007.04.023"},{"key":"e_1_2_11_6_1","doi-asserted-by":"crossref","unstructured":"Brandwein M. 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