{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T11:22:20Z","timestamp":1782127340817,"version":"3.54.5"},"reference-count":74,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the preoperative haemoglobin, albumin, lymphocyte, and platelet score as a prognostic indicator in oral squamous cell carcinoma treated by radical surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>Patients (83 men, 32 women; 65.80\u2009\u00b1\u200911.47\u2009years) who underwent radical surgery between 2012 and 2022 were included. Factors affecting overall survival and disease\u2010free survival according to the haemoglobin, albumin, lymphocyte, and platelet score were examined. Patients were categorised into low\u2010 and high\u2010score groups using optimal cut\u2010off values obtained from receiver operating characteristic curve analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The low\u2010score group had poorer overall and disease\u2010free survival (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 each). Multivariate analysis identified alcohol consumption (hazard ratio [HR], 3.83; 95% confidence interval [CI]: 1.56\u20139.41,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003); vascular invasion (HR, 3.97; 95% CI: 1.60\u20139.85,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003); and the haemoglobin, albumin, lymphocyte, and platelet score (HR, 0.39; 95% CI: 0.20\u20130.78,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) as independent prognostic factors for overall survival and vascular (HR, 3.66; 95% CI: 1.79\u20137.50,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and lymphovascular (HR, 2.44; 95% CI: 1.36\u20134.41,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) invasion as independent prognostic factors for disease\u2010free survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The preoperative haemoglobin, albumin, lymphocyte, and platelet score may be a significant prognostic factor for patients with oral squamous cell carcinoma undergoing radical surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14950","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T23:34:57Z","timestamp":1712100897000},"page":"4855-4866","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of preoperative haemoglobin, albumin, lymphocyte, and platelet score on oral cancer prognosis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9896-7660","authenticated-orcid":false,"given":"Yu","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, School of Dentistry Aichi\u2010Gakuin University  Nagoya Japan"},{"name":"Department of Oral and Maxillofacial Surgery Nagoya Ekisaikai Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4545-9117","authenticated-orcid":false,"given":"Atsushi","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Nagoya Ekisaikai Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Nagoya Ekisaikai Hospital  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,2]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903\u2010021\u201001394\u20106"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601886"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/86.11.829"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2005.09.006"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010020\u20106604\u20102"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191275"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2015.432"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2010.02.006"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100036\u20101587318"},{"key":"e_1_2_13_11_1","volume-title":"TNM classification of malignant tumours","author":"Brierley J. 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