{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:48:56Z","timestamp":1747187336301,"version":"3.40.5"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:00:00Z","timestamp":1712016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to quantify the submandibular gland in suppurative sialadenitis, primary Sj\u00f6gren's syndrome (pSS) and radiation\u2010induced sialadenitis using the apparent diffusion coefficient (ADC) for differential diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>This retrospective study included 16 patients with suppurative sialadenitis (<jats:italic>n<\/jats:italic>\u2009=\u20099), pSS (<jats:italic>n<\/jats:italic>\u2009=\u20093) and radiation\u2010induced sialadenitis (<jats:italic>n<\/jats:italic>\u2009=\u20094) who underwent magnetic resonance imaging between June 2006 and May 2022. The ADC of the submandibular glands in each state was calculated, and the differences were analysed using a one\u2010way analysis of variance and Tukey's post hoc test. Receiver operating characteristic curves were used to assess the ability of the ADC to distinguish each condition. Statistical significance was set at <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean ADC value (\u00d710<jats:sup>\u22123<\/jats:sup>\u2009mm<jats:sup>2<\/jats:sup>\/s)\u2009\u00b1\u2009standard deviation in the control (non\u2010affected side of the suppurative sialadenitis group), suppurative sialadenitis, pSS and radiation\u2010induced groups were 0.94\u2009\u00b1\u20090.16, 1.24\u2009\u00b1\u20090.16, 1.33\u2009\u00b1\u20090.13 and 1.5\u2009\u00b1\u20090.12, respectively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The diagnostic value for distinguishing each group was \u22650.75.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>ADC values are useful for quantitatively assessing and distinguishing submandibular glands in suppurative sialadenitis, primary Sj\u00f6gren's syndrome and radiation\u2010induced sialadenitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/odi.14953","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T03:34:50Z","timestamp":1712115290000},"page":"5022-5029","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differentiation of submandibular sialadenitis based on apparent diffusion coefficient"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5764-2002","authenticated-orcid":false,"given":"Hirotaka","family":"Muraoka","sequence":"first","affiliation":[{"name":"Department of Radiology Nihon University School of Dentistry 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