{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:09:45Z","timestamp":1791310185828,"version":"4.3.1"},"reference-count":30,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003451","name":"Euskal Herriko Unibertsitatea","doi-asserted-by":"publisher","award":["GUI21\/042"],"award-info":[{"award-number":["GUI21\/042"]}],"id":[{"id":"10.13039\/501100003451","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015068","name":"Universidade de Santiago de Compostela","doi-asserted-by":"publisher","award":["GI 1319"],"award-info":[{"award-number":["GI 1319"]}],"id":[{"id":"10.13039\/501100015068","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the clinicopathological and evolutionary profile of the main locations of oral squamous cell carcinoma (OSCC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>This is a retrospective study on 133 patients treated for OSCC. The group was composed of 48 women and 85 men, with a mean age 63.9\u2009\u00b1\u200912.73\u2009years. Most cases involved the lingual border of tongue (63), followed by the gingiva (36) and the floor of mouth (34). A comparative analysis was performed using multinomial regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were significant differences regarding age, sex, tobacco and alcohol consumption, liver pathology, oral potentially malignant disorders, and bone and perineural invasion. In multivariate regression, tobacco consumption, and bone invasion remained significant. There were no significant differences in relation to prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The location of OSCC is an important factor in the clinicopathological assessment of this neoplasm. The main locations of OSCC show differential etiopathogenic and clinicopathological aspects. Tobacco consumption has a great relevance in the floor of mouth; nonetheless, it is less important in the tongue border and the gum, which suggests other pathogenic factors. It is necessary to consider the anatomical location of OSCC in preventive protocols, with the aim of reducing its high mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.14971","type":"journal-article","created":{"date-parts":[[2024,5,2]],"date-time":"2024-05-02T00:40:15Z","timestamp":1714610415000},"page":"4939-4947","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparative clinicopathological study of the main anatomic locations of oral squamous cell carcinoma"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7708-0446","authenticated-orcid":false,"given":"I\u00f1aut","family":"Amezaga\u2010Fernandez","sequence":"first","affiliation":[{"name":"Department of Stomatology University of the Basque Country (UPV\/EHU)  Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7822-0968","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Aguirre\u2010Urizar","sequence":"additional","affiliation":[{"name":"Department of Stomatology University of the Basque Country (UPV\/EHU)  Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Manuel","family":"Su\u00e1rez\u2010Pe\u00f1aranda","sequence":"additional","affiliation":[{"name":"Department or Forensic Sciences and Pathology, Faculty of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Department of Pathology Clinical Hospital  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cintia","family":"Chamorro\u2010Petronacci","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria de Santiago (IDIS)  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Lafuente\u2010Ib\u00e1\u00f1ez de Mendoza","sequence":"additional","affiliation":[{"name":"Department of Stomatology University of the Basque Country (UPV\/EHU)  Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xabier","family":"Marichalar\u2010Mendia","sequence":"additional","affiliation":[{"name":"Department of Nursery I University of the Basque Country (UPV\/EHU)  Leioa Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Manuel","family":"Somoza\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"Blanco\u2010Carri\u00f3n","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Ant\u00fanez\u2010L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department or Forensic Sciences and Pathology, Faculty of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Department of Pathology Clinical Hospital  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abel","family":"Garc\u00eda\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Dentistry University of Santiago de Compostela  Santiago de Compostela Spain"},{"name":"Maxillofacial Surgery Service Complejo Hospitalario Universitario de Santiago  Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2019.152670"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.26047"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.23913"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600\u20100714.2003.00167.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2005.11.094"},{"issue":"6","key":"e_1_2_11_7_1","first-page":"E344","article-title":"Prognostic significance of the anatomical location and TNM clinical classification in oral squamous cell carcinoma","volume":"13","author":"Ara\u00fajo R. F.","year":"2008","journal-title":"Medicina Oral, Patologia Oral Y Cirugia Bucal"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2018.09.004"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-88441-7"},{"key":"e_1_2_11_10_1","volume-title":"WHO classification of head and neck Tumours","author":"El\u2010Naggar A. K.","year":"2017"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27490"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13194843"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40902\u2010015\u20100047\u20108"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.07.023"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.13246"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2019.01.007"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201095007\u20105"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010017\u201008022\u2010w"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2021.105210"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2017.08.362"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100714.2010.00984.x"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010022\u201004584\u2010w"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/1679\u2010775720130317"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0b013e3283592cce"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599818756815"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2017.04.012"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13704"},{"key":"e_1_2_11_28_1","first-page":"1358","article-title":"Multiple primary malignant tumors. A survey of the literature and a statistical study","volume":"16","author":"Warren S.","year":"1932","journal-title":"American Journal of Cancer"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13015"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27266"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2019.02.001"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.14971","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T09:45:29Z","timestamp":1733132729000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.14971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":30,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1111\/odi.14971"],"URL":"https:\/\/doi.org\/10.1111\/odi.14971","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/ODI.14971\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v2\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v3\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v3\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ODI.14971\/v3\/review1","asserted-by":"object"}]},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"2023-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}