{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:53:57Z","timestamp":1772160837973,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T00:00:00Z","timestamp":1720569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Robotic transoral mucosectomy of the base of tongue was introduced as a diagnostic procedure in patients treated for head and neck cancer with unknown primary (CUP), increasing the identification rate of the primary tumour. For the treatment of CUP, a considerable percentage of patients require adjuvant (chemo)radiation. The aim of this study was to investigate swallowing outcomes among CUP patients after TORS and adjuvant treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>A systematic review was carried out on studies investigating the impact of TORS and adjuvant treatment on swallowing\u2010related outcomes among CUP patients In addition, a cross\u2010sectional study was carried out on swallowing problems (measured using the SWAL\u2010QOL questionnaire) among CUP patients in routine care who visited the outpatient clinic 1\u20135\u2009years after TORS and adjuvant treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The systematic review (6 studies;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200998) showed that most patients returned to a full oral diet. The cross\u2010sectional study (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200912) showed that all patients were able to return to a full oral diet, nevertheless, 50% reported swallowing problems in daily life (SWAL\u2010QOL total score \u226514).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although after TORS and adjuvant treatment for CUP a full oral diet can be resumed, patients still experience problems with eating and drinking in daily life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.15063","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T02:29:52Z","timestamp":1720664992000},"page":"4830-4837","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Swallowing outcomes after transoral robotic surgery and adjuvant treatment in unknown primary"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3118-6928","authenticated-orcid":false,"given":"Fennetta A.","family":"van der Scheer","sequence":"first","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"},{"name":"Cancer Center Amsterdam (CCA), Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0111-0557","authenticated-orcid":false,"given":"Femke","family":"Jansen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"},{"name":"Cancer Center Amsterdam (CCA), Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8409-1146","authenticated-orcid":false,"given":"Simone E. J.","family":"Eerenstein","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2010 Head and Neck Surgery, Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"},{"name":"Cancer Center Amsterdam (CCA), Amsterdam UMC Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9609-1784","authenticated-orcid":false,"given":"Marije R.","family":"Vergeer","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Cancer Center Amsterdam Amsterdam UMC, VUmc  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7887-083X","authenticated-orcid":false,"given":"C. 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