{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T16:45:08Z","timestamp":1781196308197,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T00:00:00Z","timestamp":1722729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aim of this study was to identify risk factors for sialolithiasis patients using a large community and hospital\u2010based cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective case\u2013control study was conducted on 20,396 individuals, including 5100 sialolithiasis patients and 15,296 matched controls. Demographics and laboratory data were obtained from electronic medical records. Statistical analyses were performed to identify significant differences between the two groups. A\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value of &lt;0.05 was considered significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sialolithiasis was more prevalent in women, with a mean age at diagnosis of 55.75\u2009years. Several geographic location variables emerged as risk factors for sialolithiasis including Israeli birth, higher socioeconomic communities, and specific areas of residency. Tobacco smoking (odds ratio\u2009=\u20091.46) was a significant risk factor. Low high\u2010density lipoprotein levels, elevated triglycerides, and elevated amylase levels were associated with sialolithiasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study provides valuable insights into the demographic and laboratory characteristics of sialolithiasis patients, indicating that area of residency and lifestyle factors contribute to the risk of developing sialolithiasis. The findings may contribute to a better understanding of the disease and the development of preventative measures or early diagnostics tools.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.15095","type":"journal-article","created":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T01:44:21Z","timestamp":1722822261000},"page":"503-509","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Characteristics of sialolithiasis in Israel, a big\u2010data retrospective study of 5100 cases"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8780-6979","authenticated-orcid":false,"given":"Ehud","family":"Jonas","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Maurice and Gabriela Goldschleger School of Dental Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Oral and Maxillofacial Surgery Rabin Medical Center  Petah Tiqwa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Muchnik","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Maurice and Gabriela Goldschleger School of Dental Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Oral and Maxillofacial Surgery Rabin Medical Center  Petah Tiqwa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idan","family":"Rabinovich","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Maurice and Gabriela Goldschleger School of Dental Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Oral and Maxillofacial Surgery Rabin Medical Center  Petah Tiqwa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daya","family":"Masri","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Maurice and Gabriela Goldschleger School of Dental Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Oral and Maxillofacial Surgery Rabin Medical Center  Petah Tiqwa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavriel","family":"Chaushu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Maurice and Gabriela Goldschleger School of Dental Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Oral and Maxillofacial Surgery Rabin Medical Center  Petah Tiqwa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5111-8496","authenticated-orcid":false,"given":"Gal","family":"Avishai","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery The Maurice and Gabriela Goldschleger School of Dental Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Oral and Maxillofacial Surgery Rabin Medical Center  Petah Tiqwa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01074.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-020-03750-2"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/615375"},{"key":"e_1_2_10_5_1","volume-title":"StatPearls [Internet]","author":"Hammett J. 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