{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:29:00Z","timestamp":1791048540808,"version":"4.1.0"},"reference-count":60,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To investigate the effect of adiposity status, salivary physicochemical parameters, and inflammatory biomarkers on the salivary abundance of the two main cariogenic bacteria\n                      <jats:italic>Streptococcus mutans<\/jats:italic>\n                      and\n                      <jats:italic>Streptococcus sobrinus<\/jats:italic>\n                      among Hong Kong adolescents.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>\n                      This study included 180 adolescents aged 12\u201315\u2009years from Hong Kong local secondary schools. Anthropometric measurements and oral health examinations were performed. Saliva samples were collected to measure salivary physicochemical parameters, protein biomarker levels, and salivary abundance of\n                      <jats:italic>Streptococcus mutans<\/jats:italic>\n                      ,\n                      <jats:italic>Streptococcus sobrinus<\/jats:italic>\n                      , and total bacteria.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Adolescents with general overweight\/obesity or central obesity had significantly higher salivary\n                      <jats:italic>Streptococcus mutans<\/jats:italic>\n                      abundance and total bacterial load, lower stimulated salivary flow rate, and lower secretory phospholipase A\n                      <jats:sub>2<\/jats:sub>\n                      group IIA levels than the lean controls. Adolescents with general overweight\/obesity (OR\u2009=\u20093.33; 95% CI: 1.28\u20138.65) and those with central obesity (OR\u2009=\u20092.47; 95% CI: 1.02\u20136.00) had a significantly higher chance of having high salivary abundance of\n                      <jats:italic>Streptococcus mutans<\/jats:italic>\n                      than the lean controls after adjusting for confounders, with a similar detection rate of salivary\n                      <jats:italic>Streptococcus sobrinus<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      General overweight or obesity and central obesity were associated with a high salivary abundance of\n                      <jats:italic>Streptococcus mutans<\/jats:italic>\n                      but had no significant effect on salivary\n                      <jats:italic>Streptococcus sobrinus<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.15111","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T15:07:10Z","timestamp":1724339230000},"page":"2943-2953","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effect of adiposity status on salivary\n                    <i>Streptococcus mutans<\/i>\n                    and\n                    <i>Streptococcus sobrinus<\/i>"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3912-7688","authenticated-orcid":false,"given":"Qianyi","family":"Deng","sequence":"first","affiliation":[{"name":"Paediatric Dentistry and Orthodontics, Faculty of Dentistry The University of Hong Kong  Hong Kong SAR China"},{"name":"Hospital of Stomatology, Guanghua School of Stomatology Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Guangdong Provincial Key Laboratory of Stomatology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3411-6442","authenticated-orcid":false,"given":"Hai Ming","family":"Wong","sequence":"additional","affiliation":[{"name":"Paediatric Dentistry and Orthodontics, Faculty of Dentistry The University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6117-3173","authenticated-orcid":false,"given":"Simin","family":"Peng","sequence":"additional","affiliation":[{"name":"Paediatric Dentistry and Orthodontics, Faculty of Dentistry The University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"issue":"4","key":"e_1_2_11_2_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental Journal"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.00429"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601237"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802034"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18073551"},{"key":"e_1_2_11_7_1","volume-title":"The first Hong Kong population\u2010based food consumption survey","author":"Centre for Food Safety","year":"2010"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/cdli.9.4.892\u2010897.2002"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.320.7244.1240"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3402\/jom.v6.26189"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102458\u201011\u2010505"},{"key":"e_1_2_11_12_1","first-page":"1083","article-title":"Salivary profile and its correlation with dental caries and\/or obesity","volume":"101","author":"Deng Q.","year":"2022","journal-title":"Journal of Dental Research"},{"key":"e_1_2_11_13_1","volume-title":"Saliva and oral health","author":"Edgar W. 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