{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:02:50Z","timestamp":1791525770908,"version":"4.3.4"},"reference-count":65,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:00:00Z","timestamp":1734048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:00:00Z","timestamp":1734048000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the relationship between biological, psychological, and social factors underlying Burning Mouth Syndrome (BMS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>\n                      A case (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200940) and control (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200942) study containing 80 variables was examined using two network models based on regularized partial correlations (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200982).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The structure of the associative pathways with the BMS was revealed. Direct associations involved Gastrointestinal Alterations (0.23), Vitamin D Deficiency (0.29), Musculoskeletal Alterations (0.29), Symptom Severity Score 2 (SSS2) (0.22), Cortisol Variation (0.10), Interpersonal Sensitivity (0.04), Hostility (0.03). Global Severity Index, Symptom Severity Score 1, Psychoticism, Obsession\u2010Compulsion, Depression, Anxiety, and Somatization were indirectly related. The SSS2 was the most influential on BMS accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Gastrointestinal alterations and\u00a0vitamin D deficiency show a significant influence on BMS while cortisol mediates in multiple associative pathways between musculoskeletal alterations, gastrointestinal alterations, vitamin D deficiency, non\u2010restorative sleep, fatigue, and cognitive problems. In addition to anxiety and depression, psychoticism, interpersonal sensitivity, and hostility stand out as psychological factors that seem to be related to a lack of vitamin D. None of the factors studied seem to have a relevant predictive potential for BMS, except for nonspecific symptoms of central sensitization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.15219","type":"journal-article","created":{"date-parts":[[2024,12,14]],"date-time":"2024-12-14T01:48:55Z","timestamp":1734140935000},"page":"1861-1875","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Burning Mouth Syndrome Underlying Factors: A Roadmap From a Network Perspective"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2547-2296","authenticated-orcid":false,"given":"Oscar Gabriel","family":"Casta\u00f1o\u2010Joaqui","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Jim\u00e9nez Ortega","sequence":"additional","affiliation":[{"name":"Department of Psychobiology and Behavioral Sciences Methods, Faculty of Odontology Complutense University of Madrid  Madrid Spain"},{"name":"Center of Human Evolution and Behavior UCM\u2010ISCIII  Madrid Spain"},{"name":"Psychology and Orofacial Pain Working Group Sociedad Espa\u00f1ola de Disfunci\u00f3n Craneomandibular y Dolor Orofacial (SEDCYDO)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roc\u00edo","family":"Cerero Lapiedra","sequence":"additional","affiliation":[{"name":"Department of Odontologic Clinic Specialty, Faculty of Odontology Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Monteser\u00edn Matesanz","sequence":"additional","affiliation":[{"name":"Universidad Europea de Madrid, Faculty of Biomedical and Health Sciences University Dental Clinics, Villaviciosa de Od\u00f3n  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaida \u00c1frica","family":"Dom\u00ednguez Gordillo","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Public Health and History of Science, Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12807"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph20010682"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.58033"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.14051"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2019.194418"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pri.1968"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417738202"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13116"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.727417"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/joor.13343"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11092516"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.08.019"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afaa063"},{"issue":"1","key":"e_1_2_11_15_1","first-page":"13","article-title":"SCL\u201090: An Outpatient Psychiatric Rating Scale \u2013 Preliminary Report","volume":"9","author":"Derogatis L. 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