{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T14:05:35Z","timestamp":1775916335047,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated self\u2010reported symptoms of temporomandibular disorders, mandibular functional impairment, and obstructive sleep apnea among Dutch adults with Osteogenesis Imperfecta.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional online survey was distributed among Dutch adults with Osteogenesis Imperfecta. Possible risk factors for self\u2010reported temporomandibular disorders (3Q\/TMD; DC\/TMD), mandibular impairments (Mandibular Function Impairment Questionnaire), and obstructive sleep apnea (STOP\u2010Bang) were explored using univariate and multiple regression analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>31% of 155 respondents reported temporomandibular disorder symptoms and 40.0% and 5.2% moderate and severe mandibular function impairment, respectively. Intermediate and severe risk for obstructive sleep apnea were reported by 16.1% and 14.8%, respectively. Female gender and Osteogenesis Imperfecta type III were independently associated with the presence of self\u2010reported temporomandibular disorders. Osteogenesis Imperfecta type III, missing teeth, and self\u2010reported temporomandibular disorders were independently associated with impaired mandibular function. Higher age, male gender, and bisphonate use were independently associated with a higher risk for positive screening for obstructive sleep apnea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A substantial proportion of Dutch adults with Osteogenesis Imperfecta reported symptoms indicative of temporomandibular disorders, mandibular function impairment, and higher risk for obstructive sleep apnea. Especially Osteogenesis Imperfecta type III patients are at risk for self\u2010reported temporomandibular disorders and hampered mandibular function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.15280","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T23:34:43Z","timestamp":1741736083000},"page":"1909-1921","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporomandibular Dysfunction and Sleep Apnea in Dutch Adults With Osteogenesis Imperfecta"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7215-6709","authenticated-orcid":false,"given":"L.","family":"Blokland","sequence":"first","affiliation":[{"name":"Vogellanden Center of Rehabilitation Medicine &amp; Special Care in Dentistry  Zwolle the Netherlands"},{"name":"Department of Dentistry Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7336-0327","authenticated-orcid":false,"given":"E.","family":"de Kuijper\u2010Timmermans","sequence":"additional","affiliation":[{"name":"Vogellanden Center of Rehabilitation Medicine &amp; Special Care in Dentistry  Zwolle the Netherlands"},{"name":"Department of Oral and Maxillofacial Surgery University of Groningen, University Medical Center Groningen  Groningen the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"de Kuijper","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry The University of Groningen, University Medical Center Groningen, Center for Dentistry and Oral Hygiene  Groningen the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Gooijer","sequence":"additional","affiliation":[{"name":"Expert Center for Adults With Osteogenesis Imperfecta Isala Hospital  Zwolle the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. J.","family":"Harsevoort","sequence":"additional","affiliation":[{"name":"Expert Center for Adults With Osteogenesis Imperfecta Isala Hospital  Zwolle the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. C.","family":"Zillikens","sequence":"additional","affiliation":[{"name":"Erasmus MC Bone Center, Department of Internal Medicine Erasmus University Medical Center  Rotterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. M.","family":"Appelman\u2010Dijkstra","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division Endocrinology and Center for Bone Quality Leiden University Medical Center  Leiden the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. J. 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