{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:40:39Z","timestamp":1790775639565,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T00:00:00Z","timestamp":1747094400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100016018","name":"Universidad El Bosque","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016018","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess changes in periodontal status and factors related to periodontitis progression in acute coronary syndrome patients who undergo a cardiovascular rehabilitation program following an acute coronary incident.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Fifty\u2010two acute coronary syndrome patients with periodontitis were evaluated during a six\u2010month follow\u2010up period. Periodontal indices were taken at baseline and at 3 and 6\u2009months. Progression of periodontitis was established as clinical attachment loss &gt;\u20093\u2009mm in two or more teeth at nonadjacent sites. Baseline clinical conditions, microbiological concentration of subgingival biofilm, and risk factors for cardiovascular disease were associated with the incidence of periodontitis progression by a linear mixed\u2010effects model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      57.69% of the patients had severe periodontitis upon admission, and 64.58% presented a progression of periodontitis during the follow\u2010up periods. Hypertension, low HDL, and high levels of\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. forsythia<\/jats:italic>\n                      <\/jats:styled-content>\n                      in patients with elevated total cholesterol were the best predictors of clinical attachment loss, with a predictability of 99%. At 6\u2009months, 35.41% of patients' high\u2010sensitivity C\u2010reactive protein (hs\u2010CRP) levels remained over the cardiovascular risk range.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Periodontal condition deterioration was observed. Hypertension and poor metabolic control were associated with the progression of periodontitis.\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>T. forsythia<\/jats:italic>\n                      <\/jats:styled-content>\n                      was the most critical local factor in periodontitis progression.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.15382","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:45:07Z","timestamp":1747187107000},"page":"3167-3178","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Periodontitis Progression During Cardiac Rehabilitation After Acute Coronary Syndrome: Cohort Study"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4714-1292","authenticated-orcid":false,"given":"Sandra Bibiana","family":"Moscoso","sequence":"first","affiliation":[{"name":"Magister Oral Science Program, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"},{"name":"Unit of Basic Oral Investigation\u2010UIBO, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6126-5713","authenticated-orcid":false,"given":"Fernan","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1846-7448","authenticated-orcid":false,"given":"Diana Marcela","family":"Castillo","sequence":"additional","affiliation":[{"name":"Unit of Basic Oral Investigation\u2010UIBO, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8842-549X","authenticated-orcid":false,"given":"Nathaly","family":"Delgadillo","sequence":"additional","affiliation":[{"name":"Unit of Basic Oral Investigation\u2010UIBO, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2672-2488","authenticated-orcid":false,"given":"Tammy Goretty","family":"Trujillo","sequence":"additional","affiliation":[{"name":"Unit of Basic Oral Investigation\u2010UIBO, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8890-6250","authenticated-orcid":false,"given":"David","family":"Diaz\u2010Baez","sequence":"additional","affiliation":[{"name":"Unit of Basic Oral Investigation\u2010UIBO, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6675-6789","authenticated-orcid":false,"given":"Nestor","family":"Rios\u2010Osorio","sequence":"additional","affiliation":[{"name":"Biomedical Sciences Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5535-6536","authenticated-orcid":false,"given":"Juan Manuel","family":"Sarmiento","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Cl\u00ednica Shaio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3986-0625","authenticated-orcid":false,"given":"Gloria In\u00e9s","family":"Lafaurie","sequence":"additional","affiliation":[{"name":"Unit of Basic Oral Investigation\u2010UIBO, School of Dentistry Universidad El Bosque  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e318256f1e0"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.52128"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1206531"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(21)02391\u20106"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.11.4950\u20104954.2003"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsim.2005.03.011"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000167525.69400.9c"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/femspd\/ftv009"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/biology11020272"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz646"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.5.740"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090499"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867331666230726140736"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.140520"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976\u2010237X.137959"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10081938"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.2741\/s405"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060301"},{"issue":"2","key":"e_1_2_12_20_1","first-page":"97","article-title":"Periodontal Disease in Acute Coronary Syndrome Patients","volume":"34","author":"Gu Y.","year":"2021","journal-title":"American Journal of Dentistry"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1250263"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24097910"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.101535"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.25100\/cm.v44i2.1123"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.18\u20100179"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010021\u201003838\u20103"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.004406"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.5051\/jpis.2018.48.1.60"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e318277728c"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu058"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/595981"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12214"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2013.2600"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2017.12.007"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.706432"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051x.2004.00608.x"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.61758"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573397113666170407161520"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1590\/0103\u20106440202204914"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515602693"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2012.0063"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2020.5218"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090170"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569\u2010021\u201000611\u20107"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12171"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/eos.12239"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2005.00822.x"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.18\u20100006"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13853"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2021.11.009"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0902\u20100055.2004.00142.x"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.585917"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784\u2010022\u201004439\u20104"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.15382","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/odi.15382","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.15382","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T20:39:25Z","timestamp":1769719165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.15382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,13]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/odi.15382"],"URL":"https:\/\/doi.org\/10.1111\/odi.15382","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,13]]},"assertion":[{"value":"2025-01-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}