{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T13:56:26Z","timestamp":1792245386915,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T00:00:00Z","timestamp":1753488000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Endometriosis is a chronic estrogen\u2010dependent gynecological disease affecting millions of women worldwide. Besides its well\u2010established impact on reproductive health, emerging evidence suggests a potential association between endometriosis and periodontal disease. The present study discusses the interplay between the two diseases, exploring shared immunopathological mechanisms, including chronic inflammation, hormonal imbalance, and immune system modulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A 45\u2010question standardized questionnaire was answered by 4072 women clinically diagnosed with endometriosis to identify self\u2010reported periodontal status, oral hygiene habits, and systemic symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Findings report that more severe stages of endometriosis are related to increased awareness of periodontal disease, greater gingival bleeding, xerostomia, and mucosal alterations. Moreover, greater diagnostic latency aggravates both systemic and oral disorders, supporting the necessity of early treatment. These findings highlight the need for a single, multidisciplinary standard of patient care involving gynecologists, dentists, dental hygienists, and other healthcare providers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>By connecting gynecological and dental care, this study aims to promote awareness, facilitate early diagnosis, and improve quality of life for women suffering from endometriosis. Future research must explore mechanisms linking the conditions and assess therapeutic approaches to alleviate oral health issues in these individuals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70044","type":"journal-article","created":{"date-parts":[[2025,7,26]],"date-time":"2025-07-26T18:58:05Z","timestamp":1753556285000},"page":"201-215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Endometriosis\u2010Associated Periodontal Disease: A Large Cohort Perspective Study"],"prefix":"10.1111","volume":"32","author":[{"given":"Maria Teresa","family":"Agneta","sequence":"first","affiliation":[{"name":"Italian Association of Dental Hygienists (AIDI)  Bari Italy"},{"name":"Interdisciplinary Department of Medicine Department of Dentistry, University of Bari Aldo Moro  Bari 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