{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:11:14Z","timestamp":1791871874616,"version":"4.3.4"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Backgrounds<\/jats:title>\n                    <jats:p>Ameloblastic carcinoma, a rare malignant odontogenic tumor, is difficult to diagnosis and treat. Here, we retrospectively analyzed its epidemiology, prognosis, and atypical ameloblastoma, a lesion insufficient to diagnose as ameloblastic carcinoma, to provide insights for understanding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 23 cases of ameloblastic carcinoma and 31 of atypical ameloblastoma from 2004 to 2024. Epidemiology, clinical symptoms, radiographic features, treatment, and prognosis were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Regarding ameloblastic carcinoma, 15 males and 8 females ranging from 21 to 85\u2009years old were included, with an average of 51.57. Eleven cases (47.8%) occurred in the maxilla. The main symptom was swelling, and the radiographic features included honeycomb\u2010like features. The prognosis was revealed during the 1\u2010 to 19\u2010year follow\u2010up; 11 patients did not experience recurrence, 4 experienced recurrence, 7 died, and 1 was missing. The prognosis analysis revealed site, type and therapy without flap repair might be associated with recurrence, suggesting prompt extended resection might be the preferred treatment. Among patients with atypical ameloblastoma, 2 patients subsequently developed ameloblastic carcinoma, and 5 experienced recurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ameloblastic carcinoma, a rare malignant tumor with high recurrence and mortality rates, and atypical ameloblastoma with a potential for malignancy should receive prompt treatment and rigorous follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70108","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T10:40:30Z","timestamp":1759228830000},"page":"528-535","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Epidemiology and Prognosis of Ameloblastic Carcinoma: A\u00a020\u2010Year Single\u2010Center Retrospective Study"],"prefix":"10.1111","volume":"32","author":[{"given":"Zi\u2010Han","family":"Dang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology Wuhan University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao\u2010Min","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology Wuhan University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin\u2010Yu","family":"Dou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology Wuhan University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun\u2010Yu","family":"Feng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology Wuhan University  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi\u2010Han","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology Wuhan University  Wuhan 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Provincial Clinical Research Center for Oral and Maxillofacial Surgical Diseases  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4884-8129","authenticated-orcid":false,"given":"Zheng\u2010Jun","family":"Shang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology Wuhan University  Wuhan China"},{"name":"Department of Oral and Maxillofacial Head Neck Surgery, School and Hospital of Stomatology Wuhan University  Wuhan China"},{"name":"Hubei Provincial Clinical Research Center for Oral and Maxillofacial Surgical Diseases  Wuhan China"},{"name":"Taikang Center for Life and Medical Sciences of Wuhan University  Wuhan 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