{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T17:55:36Z","timestamp":1790013336100,"version":"4.0.1"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T00:00:00Z","timestamp":1763164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T00:00:00Z","timestamp":1763164800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Patients with burning mouth syndrome (BMS) suffer from oral pain in the absence of oral lesions. Although less frequently, they may also experience extraoral symptoms that are not readily apparent to clinicians. This study aimed to systematically assess the prevalence of associated extraoral symptoms and comorbid disorders in BMS patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Comprehensive searches were performed in five electronic databases (PubMed, Web of Science, Scopus, Embase, and LILACS). Observational studies that reported extraoral symptoms in primary BMS patients were included. The collected data were analyzed descriptively. The quality assessment of the included studies was conducted using the Joanna Briggs Institute tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 22 studies encompassing 2786 BMS patients. Most patients were female (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092138; 76.7%). BMS\u2010associated extraoral symptoms and comorbidities disorders included sleep disturbances (71.8%), anxiety (65.7%), depression (60.6%), alexithymia (6.1%), tinnitus (5.9%), low back pain (45.3%), and headache (4.4%). Fifteen studies were classified as low risk, six as moderate risk, and one as high risk of bias.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>BMS patients experience associated extraoral symptoms and comorbid disorders in addition to intraoral pain. These symptoms must be taken into account by clinicians and receive appropriate clinical treatment, as they can significantly affect patients\u2019 quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70144","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T16:29:51Z","timestamp":1763224191000},"page":"675-683","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of Associated Extraoral Symptoms and Comorbidities in Burning Mouth Syndrome Patients: A Systematic Review"],"prefix":"10.1111","volume":"32","author":[{"given":"Jo\u00e3o Paulo Gon\u00e7alves","family":"de Paiva","sequence":"first","affiliation":[{"name":"Departamento de Diagn\u00f3stico Oral, Faculdade de Odontologia de Piracicaba Universidade Estadual de Campinas  S\u00e3o Paulo 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USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1966-6000","authenticated-orcid":false,"given":"Alessandro","family":"Villa","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Oncology and Dentistry, Miami Cancer Institute, Baptist Health South Florida  Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacks","family":"Jorge","sequence":"additional","affiliation":[{"name":"Departamento de Diagn\u00f3stico Oral, Faculdade de Odontologia de Piracicaba Universidade Estadual de Campinas  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2040-6617","authenticated-orcid":false,"given":"Alan Roger","family":"Santos\u2010Silva","sequence":"additional","affiliation":[{"name":"Departamento de Diagn\u00f3stico Oral, Faculdade de Odontologia de Piracicaba Universidade Estadual de Campinas  S\u00e3o Paulo 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