{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:06:07Z","timestamp":1784001967570,"version":"3.55.0"},"reference-count":69,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze the \u201ctechnology\u2010disease burden paradox\u201d of early childhood caries (ECC)\u2014its rising global prevalence despite preventive advances\u2014by examining multidimensional factors from biological mechanisms to socioecological interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This narrative review synthesized evidence from epidemiological, biological, behavioral, and policy studies (2010\u20132024) identified through systematic searches in PubMed, Web of Science, and Scopus. Inclusion criteria focused on children under 6\u2009years of age and English\u2010language studies reporting etiology, risk factors, or interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      ECC prevalence exceeds 60% in many low\u2010 and middle\u2010income countries, versus &lt;\u200940% in high\u2010income settings. Key findings include: synergistic enamel demineralization by\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>S. mutans<\/jats:italic>\n                      <\/jats:styled-content>\n                      and\n                      <jats:italic>Candida<\/jats:italic>\n                      (OR\u2009=\u20091.67); behavioral risks such as nocturnal feeding (OR\u2009=\u20093.54) and screen time &gt;\u20092\u2009h\/day (\u219160% caries); and effective policy interventions like fluoride varnish (42% reduction in caries) and sugar taxes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Controlling ECC requires integrating the Socioecological Model with Sustainable Development Goals, prioritizing equity\u2010focused upstream policies and interdisciplinary collaboration (e.g., dentistry and data science). The \u201cZero\u2010Caries Childhood\u201d vision must shift from disease management to health promotion, incorporating emerging environmental considerations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70153","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T04:47:01Z","timestamp":1763700421000},"page":"1213-1225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early Childhood Caries in Preschool Children: A Multidimensional Analysis From Biological Mechanisms to Socioecological Interventions"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1652-5364","authenticated-orcid":false,"given":"Wenxuan","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Public Health, Shenyang Medical College  Shenyang People's Republic of China"},{"name":"Shenyang Medical College  Shenyang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxin","family":"Shi","sequence":"additional","affiliation":[{"name":"Shenyang Medical College  Shenyang People's Republic of China"},{"name":"School of Medical Information Engineering, Shenyang Medical College  Shenyang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Shenyang Medical College  Shenyang People's Republic of China"},{"name":"School of Stomatology, Shenyang Medical College  Shenyang People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","first-page":"3","article-title":"Associations Between Taste Preferences and Feeding Practices on Early Childhood Caries","volume":"92","author":"Abdullah M. 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