{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:06:00Z","timestamp":1784001960347,"version":"3.55.0"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aim to investigate the association between oral hygiene habits, including frequency of toothbrushing and regularity of dental check\u2010ups, and oral cancer risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A systematic review and meta\u2010analysis was developed following the PRISMA and the MOOSE guidelines. We searched electronic databases until 4th December 2024 (CRD42021242709).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 15 studies were included. Overall, the results indicated that poor oral hygiene habits are potential risk factors for oral cancer. Compared to brushing once\/day or more, toothbrushing &lt;\u20091\/day or never significantly increased the risk for oral cancer, with an OR of 1.85 (95% CI, 1.06\u20133.22). Toothbrushing &lt;\u20092\/day compared with \u2265\u20092\/day also showed a positive association with oral cancer risk, with an OR of 1.32 (95% CI, 1.17\u20131.48). Irregular dental check\u2010ups, defined as less than once a year or never, also significantly increased oral cancer risk (OR, 1.58; 95% CI, 1.29\u20131.92).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Infrequent toothbrushing and irregular dental check\u2010ups are risk factors for oral cancer. Toothbrushing twice or more daily and visiting a dentist once a year could be recommended to reduce oral cancer risk. The study reinforces the importance of good oral health as a preventive measure in the control of oral cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70201","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T04:45:28Z","timestamp":1773722728000},"page":"1291-1299","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigating the Association Between Oral Hygiene and Oral Cancer: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5908-1437","authenticated-orcid":false,"given":"Lorena C.","family":"Mariano","sequence":"first","affiliation":[{"name":"UNIPRO, Oral Pathology and Rehabilitation Research Unit University Institute of Health Sciences (IUCS\u2010CESPU)  Gandra 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