{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T05:48:55Z","timestamp":1782193735659,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T00:00:00Z","timestamp":1782086400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study assessed the feasibility of remote halitosis diagnosis by evaluating VSC stability over 7\u2009days and their association with periodontal parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      One hundred adult patients attending a periodontal examination were included. Oral gas samples were collected using plastic syringes and analyzed by gas chromatography (OralChroma) at baseline (D0) and after 7\u2009days of storage at room temperature (D7). Hydrogen sulfide (H\n                      <jats:sub>2<\/jats:sub>\n                      S), methyl mercaptan (CH\n                      <jats:sub>3<\/jats:sub>\n                      SH), and dimethyl sulfide ((CH\n                      <jats:sub>3<\/jats:sub>\n                      )\n                      <jats:sub>2<\/jats:sub>\n                      S) were quantified. Periodontal parameters were recorded. Correlations and agreement analyses were performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At D0, 64% and 31% of patients were classified as having halitosis using thresholds of &gt;\u2009120\u2009ppb and\u2009&gt;\u2009300\u2009ppb, respectively. Mean VSC concentrations were 10.2 (33.1) ppb for H\n                      <jats:sub>2<\/jats:sub>\n                      S, 208.3 (443.2) ppb for CH\n                      <jats:sub>3<\/jats:sub>\n                      SH, and 79 (166) ppb for (CH\n                      <jats:sub>3<\/jats:sub>\n                      )\n                      <jats:sub>2<\/jats:sub>\n                      S, and increased after 7\u2009days of storage for all compounds except H\n                      <jats:sub>2<\/jats:sub>\n                      S. Only (CH\n                      <jats:sub>3<\/jats:sub>\n                      )\n                      <jats:sub>2<\/jats:sub>\n                      S showed a significant correlation between D0 and D7 measurements. Agreement between halitosis diagnoses at D0 and D7 was poor for both thresholds (Cohen's kappa &lt;\u20090.2). Associations between VSC levels and periodontal parameters were weak.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Delayed analysis of oral gas samples significantly altered VSC measurements limiting their reliability for remote halitosis diagnosis. Periodontal parameters were not strongly associated with VSC levels.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70394","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T05:41:55Z","timestamp":1782193315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the Volatile Sulfur Compound Stability in\u00a0Breath Samples for Halitosis Remote Diagnosis"],"prefix":"10.1111","author":[{"given":"Eirini","family":"Militsi","sequence":"first","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire Universit\u00e9 de Strasbourg  Strasbourg France"},{"name":"P\u00f4le de m\u00e9decine et Chirurgie Bucco\u2010Dentaires H\u00f4pitaux Universitaires de Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Reingewirtz","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire 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France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre\u2010Yves","family":"Gegout","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de Chirurgie Dentaire Universit\u00e9 de Strasbourg  Strasbourg France"},{"name":"P\u00f4le de m\u00e9decine et Chirurgie Bucco\u2010Dentaires H\u00f4pitaux Universitaires de Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9751564"},{"issue":"4","key":"e_1_2_11_3_1","first-page":"229","article-title":"Problems and Proposals for Recording Gingivitis and Plaque","volume":"25","author":"Ainamo J.","year":"1975","journal-title":"International Dental 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