{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:55:51Z","timestamp":1786121751578,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This cross\u2010sectional study aimed to evaluate the influence of vitamin D and glycaemic control on the severity of periodontitis in Cameroonian type 2 diabetics (T2D) and to identify the determinants of severe periodontitis (SP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Vitamin D concentration and blood glucose control were determined by measuring serum levels of 25(OH)D and HbA1c. Periodontal examination was conducted. Fisher's exact test was used to compare proportions and Mann Whitney's test to compare medians. Univariate and multivariate analyses were performed to determine influencing factors on the prevalence of SP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      82 T2D patients were recruited. The median age of participants was 60 (15) years, and 54.9% of them had a glycated hemoglobin level \u2265\u20097%. T2D patients with SP had significantly lower median serum 25(OH)D levels than those without SP (20.5 (7.7) ng\/mL versus 25.2 (8.8) ng\/mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.028). After logistic regression, only poor glycaemic control and age were significantly associated with the severity of periodontitis (OR: 6.81 [2.07\u201322.35]\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002; OR: 1.07 [1.01\u20131.12]\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.013), respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study highlights the negative impact of poor glycaemic control and advanced age on the periodontium. The role of vitamin D on the severity of periodontitis still needs to be defined more precisely in future studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70424","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:34:22Z","timestamp":1786084462000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of Vitamin D Concentration and Glycaemic Control on the Severity of Periodontitis in Cameroonian Type 2 Diabetics: A Cross\u2010Sectional Study"],"prefix":"10.1111","author":[{"given":"Lawrence","family":"Essama Eno Belinga","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Pharmaceutical Sciences University of Douala  Douala Cameroon"},{"name":"Biochemistry Laboratory, Faculty of Sciences University of Douala  Douala Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine Claude","family":"Etoa Etoga","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biomedical Sciences University of Yaound\u00e9 1  Yaound\u00e9 Cameroon"},{"name":"Endocrinology Department Yaound\u00e9 Central Hospital  Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merveille Grace","family":"Ngapmegne Tankio","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences University of the Mountains  Bangangt\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Williams","family":"Bell Ngan","sequence":"additional","affiliation":[{"name":"Regional military hospital N 2  Douala Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bienvenu","family":"Bongue","sequence":"additional","affiliation":[{"name":"Laboratories P2S University Claude Bernard, Lyon 1  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00f4me","family":"Ebana Mvogo","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biomedical Sciences University of Yaound\u00e9 1  Yaound\u00e9 Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francioli","family":"Koro Koro","sequence":"additional","affiliation":[{"name":"Biochemistry Laboratory, Faculty of Sciences University of Douala  Douala Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie Rosalie","family":"Ngono Ngane","sequence":"additional","affiliation":[{"name":"Biochemistry Laboratory, Faculty of Sciences University of Douala  Douala Cameroon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7988-2290","authenticated-orcid":false,"given":"Olivier","family":"Huck","sequence":"additional","affiliation":[{"name":"Dental Faculty University of Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,6]]},"reference":[{"issue":"6","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1002\/cre2.657","article-title":"Comparison of Serum Levels of Vitamin D in Periodontitis Patients With and Without Type 2 Diabetes and Healthy Subjects","volume":"8","author":"Akbari N.","year":"2022","journal-title":"Clinical and Experimental Dental Research"},{"key":"e_1_2_10_3_1","article-title":"Association Between Periodontal Diseases and Cardiovascular Diseases in Cameroon","volume":"9","author":"Belinga L. 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M.","year":"2018","journal-title":"BMJ Open Diabetes Research & Care"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.70424","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/odi.70424","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/odi.70424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T06:34:27Z","timestamp":1786084467000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/odi.70424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,6]]},"references-count":32,"alternative-id":["10.1111\/odi.70424"],"URL":"https:\/\/doi.org\/10.1111\/odi.70424","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,6]]},"assertion":[{"value":"2026-05-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"odi.70424"}}