{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T04:27:22Z","timestamp":1786508842394,"version":"build-2736575974"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To map and characterize the therapeutic strategies described in the literature for the management of microstomia in patients with systemic sclerosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This scoping review was conducted in accordance with the PRISMA\u2010ScR guidelines. Searches were performed in Medline\/PubMed, Embase, Scopus, Web of Science, Cochrane Library, and gray literature searches. Studies involving adults with systemic sclerosis of any subtype who received local or systemic interventions aimed at improving microstomia and reported at least one mouth opening\u2013related outcome were eligible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010five studies were included. Non\u2010surgical interventions predominated, including physiotherapy, injectables, and oral medications, whereas surgical treatments were less frequently reported and mainly involved autologous fat grafting. Randomized controlled trials primarily evaluated conservative interventions, while surgical approaches were mostly investigated in quasi\u2010experimental studies. Heterogeneity was observed across study designs, outcome measures, follow\u2010up durations, and assessment instruments. Objective measures of mouth opening, especially interincisal distance, were the most reported outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The available evidence on microstomia management in systemic sclerosis is predominantly based on non\u2010surgical interventions and is marked by substantial methodological heterogeneity. Future research should prioritize standardized outcome measures, longer follow\u2010up periods, and well\u2010designed multicenter studies to better define the role of conservative and surgical treatments in this clinical setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70451","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T03:33:42Z","timestamp":1786505622000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Restoring Mouth Opening in Systemic Sclerosis: A Scoping Review of Interventions"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5673-2927","authenticated-orcid":false,"given":"Beatriz Borba Barros","family":"Bernardo","sequence":"first","affiliation":[{"name":"Department of Clinical and Preventive Dentistry Federal University of Pernambuco  Recife Pernambuco 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Egito","family":"Vasconcelos","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Faculty of Dentistry University of Pernambuco (UPE)  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3154-5092","authenticated-orcid":false,"given":"Sandra L\u00facia Dantas","family":"Moraes","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation, Faculty of Dentistry University of Pernambuco (UPE)  Recife Pernambuco Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6815-5696","authenticated-orcid":false,"given":"Marianne Vasconcelos","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Oral Histopathology Research Group, Graduate Program in Dentistry, Faculty of Dentistry of Pernambuco and Integrated Center of Pathological Anatomy Oswaldo Cruz University Hospital, University of Pernambuco (UPE)  Recife 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