{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T05:24:38Z","timestamp":1787289878885,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n To estimate the incidence and predictors of oral candidiasis in patients with oral lichen planus (OLP) treated with topical corticosteroids.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Retrospective cohort study of 312 adults with OLP followed for 487.5 person\u2010years. The primary outcome was the first microbiologically confirmed episode of oral candidiasis. Adjusted incidence rate ratios (IRRs and rinses) were estimated using Poisson regression; Cox proportional hazards models were used for sensitivity analysis.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Oral candidiasis occurred in 78 patients (25.0%; incidence rate 0.160 per person\u2010year), with a median onset of 4\u2009months. Risk peaked within the first 2\u2009months and declined thereafter (IRR\u2009=\u20090.33 for 4\u20138\u2009months; IRR\u2009=\u20090.08 for >\u20098\u2009months). Higher disease severity predicted infection (highest vs. lowest quartile: IRR\u2009=\u20091.61; 95% CI: 1.02\u20132.54). Poor oral hygiene (IRR\u2009=\u20091.88; 95% CI: 1.13\u20133.13) and removable partial dentures (IRR\u2009=\u20091.68; 95% CI: 1.07\u20132.63) were independently associated. Clobetasol propionate showed a higher risk than triamcinolone acetonide (IRR\u2009=\u20091.48; 95% CI: 0.96\u20132.28); these associations remained consistent in sensitivity analysis. No associations were observed for age, sex, alcohol use or xerostomia.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Oral candidiasis is common in corticosteroid\u2010treated OLP. Risk is driven by disease severity and modifiable local factors, supporting targeted prevention and monitoring.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/odi.70470","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T04:45:54Z","timestamp":1787287554000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Candidiasis in Patients With Oral Lichen Planus Receiving Topical Corticosteroids: A Retrospective Cohort Study"],"prefix":"10.1111","author":[{"given":"Alba","family":"D\u00edaz\u2010Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9180-4703","authenticated-orcid":false,"given":"Alejandro I.","family":"Lorenzo\u2010Pouso","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9714-5518","authenticated-orcid":false,"given":"Eva Mar\u00eda","family":"Otero\u2010Rey","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"},{"name":"ORALRES Group Instituto de Investigaci\u00f3n Sanitaria de Santiago (IDIS) Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2259-7971","authenticated-orcid":false,"given":"Pilar","family":"G\u00e1ndara\u2010Vila","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"},{"name":"ORALRES Group Instituto de Investigaci\u00f3n Sanitaria de Santiago (IDIS) Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9386-784X","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Somoza\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"},{"name":"ORALRES Group Instituto de Investigaci\u00f3n Sanitaria de Santiago (IDIS) Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2196-9868","authenticated-orcid":false,"given":"Mario","family":"P\u00e9rez\u2010Say\u00e1ns","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"},{"name":"ORALRES Group Instituto de Investigaci\u00f3n Sanitaria de Santiago (IDIS) Santiago de Compostela Spain"},{"name":"Instituto de los Materiales de Santiago de Compostela (iMATUS) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7405-1834","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Blanco\u2010Carri\u00f3n","sequence":"additional","affiliation":[{"name":"Oral Medicine, Oral Surgery and Implantology Unit (MedOralRes) Faculty of Medicine and Dentistry, Universidade de Santiago de Compostela Santiago de Compostela Spain"},{"name":"ORALRES Group Instituto de Investigaci\u00f3n Sanitaria de Santiago (IDIS) Santiago de Compostela Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/jdv.12128","article-title":"Pimecrolimus vs. Tacrolimus for the Topical Treatment of Unresponsive Oral Erosive Lichen Planus: A 8 Week Randomized Double\u2010Blind Controlled Study","volume":"28","author":"Arduino P. 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