{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T06:06:41Z","timestamp":1788934001850,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n This study aimed to evaluate treatment\u2010related weight changes in oral cancer and examine their association with functional impairments, public visits, and future life perspectives.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n Data from 1359 surgically treated patients were retrospectively analyzed in a multicenter rehabilitation study conducted by the German\u2010Austrian\u2010Swiss Cooperative Group on Tumors of the Maxillofacial Region (D\u00d6SAK). Weight changes were self\u2010reported after treatment using a standardized questionnaire. Associations with tumor stage, surgical treatment, functional impairments, public visits, and future life perspectives were analyzed.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Weight loss was significantly associated with advanced tumor stage (\n p<\/jats:italic>\n \u2009=\u20090.001), nodal metastasis (\n p<\/jats:italic>\n \u2009<\u20090.001), and radical neck dissection (\n p<\/jats:italic>\n \u2009=\u20090.038). Weight differences alone did not change patients' public visits compared with the past (\n p<\/jats:italic>\n \u2009<\u20090.001). However, weight loss combined with functional impairments in eating (\n p<\/jats:italic>\n \u2009<\u20090.001), speaking (\n p<\/jats:italic>\n \u2009<\u20090.001), and physical appearance (\n p<\/jats:italic>\n \u2009<\u20090.001) was associated with avoidance of public visits. Stable weight was associated with favorable future life perspectives, whereas weight loss was associated with negative future perspectives (\n p<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Early identification of treatment\u2010related weight changes may help identify patients at risk of functional impairments and adverse psychosocial outcomes, supporting timely nutritional interventions in oral cancer care.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/odi.70495","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:16:59Z","timestamp":1788931019000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of Treatment\u2010Related Weight Changes With Functional Impairments, Public Visits, and Future Life Perspectives in Oral Cancer: A Multicenter Study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4297-3306","authenticated-orcid":false,"given":"Efthymios","family":"Papazacharias","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6703-4480","authenticated-orcid":false,"given":"Max Lukas","family":"Linderkamp","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5591-9006","authenticated-orcid":false,"given":"Stephan Alexander","family":"Bettag","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anij","family":"von der Gracht","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1814-9876","authenticated-orcid":false,"given":"Rijahd Sahmer","family":"Boustani","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8728-8662","authenticated-orcid":false,"given":"Jan","family":"Gaessler","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Lewandowski","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9871-8421","authenticated-orcid":false,"given":"Fritjof","family":"Lentge","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3461-5364","authenticated-orcid":false,"given":"Michael\u2010Tobias","family":"Neuhaus","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gertrud","family":"Kr\u00fcskemper","sequence":"additional","affiliation":[{"name":"Department of Medical Psychology Ruhr University of Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils\u2010Claudius","family":"Gellrich","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Korn","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5999-9603","authenticated-orcid":false,"given":"Philipp","family":"Jehn","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Hannover Medical School Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"issue":"5","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1002\/ohn.672","article-title":"Revisiting Feeding Tube Utilization in Oropharynx Cancer: 6\u2010Year Prospective Registry Analysis","volume":"170","author":"Anderson B. 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