{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:40:14Z","timestamp":1792471214125,"version":"4.5.0"},"reference-count":40,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T00:00:00Z","timestamp":1792368000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012542","name":"Dalin Tzu Chi Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Oral Diseases"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The COVID\u201019 pandemic disrupted cancer screening services worldwide, but its impact across multiple screening indicators remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This population\u2010based interrupted time series study evaluated the impact of COVID\u201019 on oral cancer screening in Taiwan. Two intervention points were defined: January 2020 and May 2021. Four indicators were assessed: screening rate, screening positivity rate, incidence, and mortality. Segmented regression analyses were performed across six National Health Insurance divisions, and changes in stage at diagnosis (2018\u20132022) were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At baseline, screening rates declined, screening positivity rate and mortality increased modestly, and incidence remained stable. After the first outbreak, screening positivity rate showed a significant immediate decrease (OR\u2009=\u20090.86, 95% CI: 0.81\u20130.92,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), whereas screening rate, incidence, and mortality showed no significant changes. Advanced\u2010stage diagnoses increased, while early\u2010stage diagnoses declined. Regional analyses demonstrated similar patterns. No significant slope changes after the first outbreak or level\/trend changes after the second outbreak were observed. Incidence and mortality remained stable throughout the study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The first outbreak had the greatest impact on screening\u2010related indicators, with findings consistent with possible delays in cancer detection. Maintaining organized screening services during public health emergencies is essential to minimize delayed cancer detection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/odi.70547","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T04:22:02Z","timestamp":1792470122000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of the\n                    <scp>COVID<\/scp>\n                    \u201019 Pandemic on Oral Cancer Screening: Real\u2010World Data From Taiwan"],"prefix":"10.1111","author":[{"given":"Yu\u2010Hsun","family":"Kao","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery Kaohsiung Medical University Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Nan","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Family Medicine Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation  Chiayi Taiwan"},{"name":"School of Medicine Tzu Chi University  Hualien Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu\u2010Lin","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Dentistry, College of Dental Medicine Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7056-5686","authenticated-orcid":false,"given":"Yu\u2010Ting","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Medical Statistics and Bioinformatics, Department of Medical Research Kaohsiung Medical University Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4221-9612","authenticated-orcid":false,"given":"Wen\u2010Chen","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Dentistry, College of Dental Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Cancer Research Center Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Oral and Maxillofacial Image Center, College of Dental Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Division of Oral Pathology and Oral Maxillofacial Radiology, Department of Dentistry Kaohsiung Medical University Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Wen","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Family Medicine Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation  Chiayi Taiwan"},{"name":"School of Medicine Tzu Chi University  Hualien Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0860-1690","authenticated-orcid":false,"given":"Pei\u2010Shan","family":"Ho","sequence":"additional","affiliation":[{"name":"School of Dentistry, College of Dental Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Division of Medical Statistics and Bioinformatics, Department of Medical Research Kaohsiung Medical University Hospital  Kaohsiung Taiwan"},{"name":"Department of Oral Hygiene Kaohsiung Medical University  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,19]]},"reference":[{"issue":"5","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.10946","article-title":"Socioeconomic and Racial Inequities in Breast Cancer Screening During the COVID\u201019 Pandemic in Washington State","volume":"4","author":"Amram O.","year":"2021","journal-title":"JAMA Network Open"},{"issue":"3","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1001\/jamaoncol.2020.7600","article-title":"Cancer Screening Tests and Cancer Diagnoses During the COVID\u201019 Pandemic","volume":"7","author":"Bakouny Z.","year":"2021","journal-title":"JAMA Oncology"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph21070816"},{"issue":"2","key":"e_1_2_10_5_1","doi-asserted-by":"crossref","DOI":"10.2196\/21697","article-title":"The Impact of COVID\u201019 on Cancer Screening: Challenges and Opportunities","volume":"6","author":"Cancino R. 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