{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:06:50Z","timestamp":1790791610754,"version":"4.1.0"},"reference-count":93,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T00:00:00Z","timestamp":1416355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2011-0009233"],"award-info":[{"award-number":["2011-0009233"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Oral Microbiology"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Smoking is a major environmental factor associated with periodontal diseases. However, we still have a very limited understanding of the relationship between smoking and subgingival microflora in the global population. Here, we investigated the composition of subgingival bacterial communities from the pooled plaque samples of smokers and non\u2010smokers, 134 samples in each group, in Korean patients with moderate chronic periodontitis using 16S rRNA gene\u2010based pyrosequencing. A total of 17,927 reads were analyzed and classified into 12 phyla, 126 genera, and 394 species. Differences in bacterial communities between smokers and non\u2010smokers were examined at all phylogenetic levels. The genera\n                    <jats:italic>Fusobacterium<\/jats:italic>\n                    ,\n                    <jats:italic>Fretibacterium<\/jats:italic>\n                    ,\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    ,\n                    <jats:italic>Veillonella<\/jats:italic>\n                    ,\n                    <jats:italic>Corynebacterium<\/jats:italic>\n                    , TM7, and\n                    <jats:italic>Filifactor<\/jats:italic>\n                    were abundant in smokers. On the other hand,\n                    <jats:italic>Prevotella<\/jats:italic>\n                    ,\n                    <jats:italic>Campylobacter<\/jats:italic>\n                    ,\n                    <jats:italic>Aggregatibacter<\/jats:italic>\n                    ,\n                    <jats:italic>Veillonellaceae<\/jats:italic>\n                    GQ422718,\n                    <jats:italic>Haemophilus<\/jats:italic>\n                    , and\n                    <jats:italic>Prevotellaceae<\/jats:italic>\n                    were less abundant in smokers. Among species\u2010level taxa occupying &gt;\u00a01% of whole subgingival microbiome of smokers, higher abundance (\u2265\u00a02.0\u2010fold compared to non\u2010smokers) of seven species or operational taxonomic units (OTUs) was found:\n                    <jats:italic>Fusobacterium nucleatum<\/jats:italic>\n                    ,\n                    <jats:italic>Neisseria sicca<\/jats:italic>\n                    ,\n                    <jats:italic>Neisseria oralis<\/jats:italic>\n                    ,\n                    <jats:italic>Corynebacterium matruchotii<\/jats:italic>\n                    ,\n                    <jats:italic>Veillonella dispar<\/jats:italic>\n                    ,\n                    <jats:italic>Filifactor alocis<\/jats:italic>\n                    , and\n                    <jats:italic>Fretibacterium<\/jats:italic>\n                    AY349371. On the other hand, lower abundance of 11 species or OTUs was found in smokers:\n                    <jats:italic>Neisseria elongata<\/jats:italic>\n                    , six\n                    <jats:italic>Prevotella<\/jats:italic>\n                    species or OTUs,\n                    <jats:italic>Fusobacterium canifelinum<\/jats:italic>\n                    ,\n                    <jats:italic>Aggregatibacter<\/jats:italic>\n                    AM420165,\n                    <jats:italic>Selenomonas<\/jats:italic>\n                    OTU, and\n                    <jats:italic>Veillonellaceae<\/jats:italic>\n                    GU470897. Species richness and evenness were similar between the groups whereas diversity was greater in smokers than non\u2010smokers. Collectively, the results of the present study indicate that differences exist in the subgingival bacterial community between smoker and non\u2010smoker patients with chronic moderate periodontitis in Korea, suggesting that cigarette smoking considerably affects subgingival bacterial ecology.\n                  <\/jats:p>","DOI":"10.1111\/omi.12086","type":"journal-article","created":{"date-parts":[[2014,10,6]],"date-time":"2014-10-06T04:34:24Z","timestamp":1412570064000},"page":"227-241","source":"Crossref","is-referenced-by-count":104,"title":["Subgingival microbiome in smokers and non\u2010smokers in Korean chronic periodontitis patients"],"prefix":"10.1111","volume":"30","author":[{"given":"J.\u2010H.","family":"Moon","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Biomedical Engineering School of Dentistry Institute of Oral Biology Kyung Hee University Seoul Korea"},{"name":"Department of Life and Nanopharmaceutical Sciences Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.\u2010H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Biomedical Engineering School of Dentistry Institute of Oral Biology Kyung Hee University Seoul Korea"},{"name":"Department of Life and Nanopharmaceutical Sciences Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.\u2010Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Biomedical Engineering School of Dentistry Institute of Oral Biology Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2009.01145.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1989.tb00009.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00788.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.69.807.41"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12061"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1989.tb00626.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb02253.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1983.tb01367.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1991.62.4.242"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12087"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016358609004732"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028003212.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.69.3.1687-1694.2003"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800790121"},{"key":"e_1_2_5_16_1","doi-asserted-by":"crossref","unstructured":"Chen T. 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