{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T11:03:53Z","timestamp":1768043033356,"version":"3.49.0"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Molecular Oral Microbiology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Periodontal disease, a global health concern, is strongly associated with oral treponemes. However, the taxonomy of some species remains unresolved, hindering our understanding of their roles in disease. This study aims to clarify the taxonomy of three strains isolated from patients with periodontal disease using phylogenomic and comparative genomic analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We performed genome sequencing for OMZ 800 and conducted phylogenomic and comparative genomic analyses of multiple strains to clarify their taxonomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Phylogenomic and in\u2010silico genome comparisons confirmed OMZ 800 as \u201c\n                      <jats:italic>T. vincentii<\/jats:italic>\n                      \u201d (Average Nucleotide Identity [ANI]&gt;95%). We designated OMZ 800\n                      <jats:sup>T<\/jats:sup>\n                      as the type strain for\n                      <jats:italic>T. vincentii<\/jats:italic>\n                      to establish its official standing in bacterial taxonomy. OMZ 806 (2.7 Mb, 44.9% GC) clustered with phylogroup IB strain (ANI&gt;95%\u00a0vs. OMZ 305), whereas OMZ 838 (2.7 Mb, 44.6% GC) clustered with phylogroup IA strains (ANI&gt;95%\u00a0vs. OMZ 855 and OMZ 857). Both OMZ 806 and OMZ 838 strains showed ANI&lt;95% compared to\n                      <jats:italic>T. medium<\/jats:italic>\n                      ATCC700293\n                      <jats:sup>T<\/jats:sup>\n                      , supporting their classification as novel species. We propose\u00a0\n                      <jats:italic>Treponema plautii<\/jats:italic>\n                      \u00a0sp. nov. OMZ 806\n                      <jats:sup>T<\/jats:sup>\n                      (with OMZ305 as additional strain) and\n                      <jats:italic>Treponema sinense<\/jats:italic>\n                      \u00a0sp. nov. OMZ 838\n                      <jats:sup>T<\/jats:sup>\n                      (with OMZ 855 and OMZ 857 as additional strains).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This study clarifies\n                      <jats:italic>Treponema<\/jats:italic>\n                      taxonomy by designating OMZ 800\n                      <jats:sup>T<\/jats:sup>\n                      as the type strain of\n                      <jats:italic>T. vincentii<\/jats:italic>\n                      and proposing two novel species, providing a refined taxonomical framework for this important genus.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/omi.70009","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:59:46Z","timestamp":1757703586000},"page":"26-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Genomic Insights Into the\n                    <i>Treponema<\/i>\n                    Genus: Taxonomic Resolution of\n                    <i>Treponema vincentii<\/i>\n                    and Description of Two Novel Species,\n                    <i>Treponema plautii<\/i>\n                    sp. nov. and\n                    <i>Treponema sinense<\/i>\n                    sp. nov."],"prefix":"10.1111","volume":"41","author":[{"given":"Jordan Y. H.","family":"Fong","sequence":"first","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong Special Administrative Region China"},{"name":"Department of Microbiology School of Clinical Medicine Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Man Lung","family":"Yeung","sequence":"additional","affiliation":[{"name":"Department of Microbiology School of Clinical Medicine Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"},{"name":"State Key Laboratory of Emerging Infectious Diseases Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"},{"name":"Department of Clinical Microbiology and Infection Control The University of Hong Kong\u2010Shenzhen Hospital  Shenzhen China"},{"name":"Carol Yu Centre for Infection Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsz Tuen","family":"Li","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong Special Administrative Region China"},{"name":"Department of Microbiology School of Clinical Medicine Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wing Ho","family":"Li","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanchao","family":"Ma","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong Special Administrative Region China"},{"name":"Department of Microbiology School of Clinical Medicine Li Ka Shing Faculty of Medicine The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wai Keung","family":"Leung","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry The University of Hong Kong  Hong Kong Special Administrative Region China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3912-4057","authenticated-orcid":false,"given":"Jade L. 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