{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:10:25Z","timestamp":1792631425356,"version":"4.5.0"},"reference-count":53,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T00:00:00Z","timestamp":1714694400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Older People Nursing"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The prevalence of essential hypertension contributed significantly to morbidity and mortality rates. Acupuncture\u2010related therapies were commonly employed in hypertension treatment. Nevertheless, a lack of conclusive evidence left uncertainties regarding the optimal strategies for managing hypertensive populations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Conduct a comprehensive systematic review to evaluate the existing clinical evidence about the effectiveness of acupuncture and moxibustion\u2010related therapies in managing hypertension, by employing network meta\u2010analysis techniques.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive electronic search was conducted across n of databases. This search covered studies available up to October 2022. Randomized controlled trials assessing acupuncture and moxibustion\u2010related therapies in managing hypertension based on traditional Chinese medicine were screened. Primary outcome measures included the antihypertensive effectiveness rate, variations in blood pressure and the incorporation of Traditional Chinese Medicine (TCM) syndrome manifestations. The review follows the guidelines outlined in the PRISMA statement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We identified a total of 24 trials with 1867 patients, which evaluated the efficacy of various acupuncture\u2010related therapies for hypertension management. Network meta\u2010analysis showed that moxibustion and auricular point sticking combined with medication therapy had the best effect in terms of antihypertensive effective rate (medication\u2009+\u2009moxibustion\u2009+\u2009auricular pressure vs. medication\u2009=\u20091.29 [1.09, 1.54]; sucra\u2009=\u200985.9, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) and hypertension symptom improvement (medication\u2009+\u2009moxibustion\u2009+\u2009auricular pressure vs. medication\u2009=\u2009\u22121.55 [\u22122.98, \u22120.13]; sucra\u2009=\u200996.1, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Acupuncture combined with moxibustion combined with medication therapy had the best effect in reducing systolic pressure (medication\u2009+\u2009moxibustion\u2009+\u2009acupuncture vs. medication\u2009=\u2009\u22128.50 [\u221210.19, \u22126.80]; sucra\u2009=\u2009100, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) and diastolic blood pressure (medication\u2009+\u2009moxibustion\u2009+\u2009acupuncture versus medication\u2009=\u2009\u22124.72 [\u22126.71, \u22122.72]; sucra\u2009=\u200999.71, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Network meta\u2010analysis suggested that the combined use of moxibustion and auricular point application in conjunction with drug therapy showed the highest likelihood of being the most effective treatment in terms of antihypertensive efficiency rates and improvement in hypertension symptoms. Furthermore, the combination of acupuncture and moxibustion alongside drug treatment emerged as the most promising approach for reducing systolic blood pressure and diastolic blood pressure. Limited by the methodological quality and quantity of the included studies, the results need to be interpreted with caution. It is necessary to conduct more high\u2010quality randomized controlled trials of acupuncture\u2010related therapies for the adjuvant treatment of hypertension in the future.<\/jats:p><\/jats:sec><jats:sec><jats:title>Implications for practice<\/jats:title><jats:p>Clinicians can use acupuncture\u2010related therapies to inform their treatment decisions and potentially incorporate acupuncture\u2010related therapies into their hypertension management protocols.<\/jats:p><\/jats:sec>","DOI":"10.1111\/opn.12613","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T18:29:48Z","timestamp":1714760988000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Intervention of hypertension by acupuncture\u2010related therapies: A network 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Yu","sequence":"additional","affiliation":[{"name":"The School of Nursing Anhui University of Chinese Medicine  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Shi","sequence":"additional","affiliation":[{"name":"The School of Nursing Anhui University of Chinese Medicine  Hefei China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahui","family":"Meng","sequence":"additional","affiliation":[{"name":"The School of Nursing Anhui University of Chinese Medicine  Hefei China"},{"name":"School of Nursing and Allied Health Sciences St. Paul University Philippines  Tuguegarao City Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Wu","sequence":"additional","affiliation":[{"name":"RWTH Aachen University  Aachen 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