{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T14:29:49Z","timestamp":1767796189038,"version":"3.49.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T00:00:00Z","timestamp":1357689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To compare the optical and visual quality of a simulated Toric Implantable Collamer Lens (\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      ) and a bioptics technique to treat high myopic astigmatism.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      An adaptive optics visual simulator was used to simulate the vision after\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      implantation and a bioptics procedure from the wavefront aberration pattern for moderate and high\u2010myopic astigmatism. Visual acuity (\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      ) at different contrasts and contrast sensitivity (\n                      <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content>\n                      ) at 10, 20 and 25 cycles degree\n                      <jats:sup>\u22121<\/jats:sup>\n                      were measured for 3 and 5\u2010mm pupils. Modulation Transfer Function (\n                      <jats:styled-content style=\"fixed-case\">MTF<\/jats:styled-content>\n                      ) and Point Spread Function (\n                      <jats:styled-content style=\"fixed-case\">PSF<\/jats:styled-content>\n                      ) were calculated for a 5\u2010mm pupil.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At a 3\u2010mm pupil we only found statistically significant differences in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      between the two simulated surgeries at low\u2010contrast for moderate\u2010 and high\u2010myopic astigmatism (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). Statistically significant differences were found in\n                      <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content>\n                      at 3\u2010mm pupil between both procedures at the highest spatial frequency for moderate\u2010myopic astigmatism and at all frequencies for high\u2010myopic astigmatism (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). At a 5\u2010mm pupil we found statistically significant differences in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content>\n                      between both simulated surgeries at all contrasts and frequencies evaluated for both groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). In all cases\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content>\n                      were better with the\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      than with the bioptics technique.\n                      <jats:styled-content style=\"fixed-case\">MTF<\/jats:styled-content>\n                      s for the bioptics technique were worse than those computed for the\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      . The\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      showed less spread out of the\n                      <jats:styled-content style=\"fixed-case\">PSF<\/jats:styled-content>\n                      than the bioptics procedure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Simulated\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      and bioptics procedures provided good optical and visual quality, although\n                      <jats:styled-content style=\"fixed-case\">TICL<\/jats:styled-content>\n                      implantation provided slightly better outcomes than the bioptics procedure, especially when the pupil diameter was increased.\n                    <\/jats:p>\n                  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