{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T14:29:51Z","timestamp":1767796191870,"version":"3.49.0"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T00:00:00Z","timestamp":1358985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>It is widely accepted that monocular deprivation results in improved visual performance in the non\u2010pathological eye. The current study investigates the effect of deprivation due to severe impairment in one eye during late childhood or adulthood, on the spatial performance of the fellow \u2018good\u2019 eye.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty patients (age: 29\u00a0\u00b1\u00a09\u00a0years) with severe visual impairment in one eye (visual acuity equal or worse than count fingers at 1\u00a0m), for a period longer than 2\u00a0years, participated in the study. Only patients with an age less than 50\u00a0years and monocular deprivation onset greater than 9\u00a0years were included. On the basis of the time of deprivation the patients were categorised into two subgroups: (i) long\u2010past deprivation (N\u00a0=\u00a08, age 28\u00a0\u00b1\u00a08\u00a0years, 9\u201320\u00a0years of deprivation) and recent deprivation (N\u00a0=\u00a012, age 30\u00a0\u00b1\u00a011\u00a0years, 2\u20134\u00a0years of deprivation). Eighteen more participants (age: 28\u00a0\u00b1\u00a05\u00a0years) with normal binocular vision served as the control group. Best\u2010corrected contrast sensitivity was evaluated using reversing (2\u00a0Hz) vertical sinusoidal gratings. Seven spatial frequencies (1, 2, 4, 8, 12, 16 and 24\u00a0c\/deg) were tested. Performance of the control group was tested both monocularly (dominant eye) and binocularly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In normal subjects, binocular viewing improved contrast sensitivity on average by 4.2\u00a0dB (corresponding to a 70% improvement in contrast threshold) compared to monocular recordings. Average contrast sensitivity in subjects with impaired vision in one eye was found to be higher by 5.0\u00a0dB (corresponding to an 83% improvement in contrast threshold) compared with the dominant eye of the control group. The increase in sensitivity was independent of spatial frequency. No differences were observed between the two subgroups with recent and long\u2010past deprivation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Notable improvement in contrast sensitivity was found in the non\u2010pathological eye of patients with severe impairment in the other eye at an age after the \u201ccritical\u201d period of visual development. These findings are consistent with growing evidence supporting functional changes as a result of altered experience or injury in the adult vision system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.12026","type":"journal-article","created":{"date-parts":[[2013,1,24]],"date-time":"2013-01-24T11:38:58Z","timestamp":1359027538000},"page":"150-156","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Contrast sensitivity in the \u2018good eye\u2019 of adult patients with severe impairment in the other eye"],"prefix":"10.1007","volume":"33","author":[{"given":"Trisevgeni","family":"Giannakopoulou","sequence":"first","affiliation":[{"name":"Institute of Vision &amp; Optics (IVO) University of Crete Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sotiris","family":"Plainis","sequence":"additional","affiliation":[{"name":"Institute of Vision &amp; Optics (IVO) University of Crete Crete Greece"},{"name":"Faculty of Life Sciences University of Manchester Manchester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis G","family":"Pallikaris","sequence":"additional","affiliation":[{"name":"Institute of Vision &amp; Optics (IVO) University of Crete Crete Greece"},{"name":"Department of Ophthalmology University Hospital of Crete Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miltiadis K","family":"Tsilimbaris","sequence":"additional","affiliation":[{"name":"Institute of Vision &amp; Optics (IVO) University of Crete Crete Greece"},{"name":"Department of Ophthalmology University Hospital of Crete Crete Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,1,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/208191a0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/152698a0"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1962.sp006837"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6989(81)90160-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6989(78)90206-7"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6989(84)90063-4"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713689609007626"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03206136"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1167\/6.11.7"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.69.1.51"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1963.26.6.978"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1965.28.6.1029"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1970.sp009022"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1977.0050"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/258199a0"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2007.10.003"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3952507"},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1152\/jn.1974.37.6.1276","article-title":"Effects of early monocular deprivation on visual input to cat superior colliculus","volume":"37","author":"Hoffmann KP","year":"1974","journal-title":"J Neurophysiol"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)91303-7"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1986.sp016298"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1978.sp012421"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901790302"},{"key":"e_1_2_7_24_1","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1152\/jn.1980.43.6.1645","article-title":"Monocularly deprived humans: nondeprived eye has supernormal vernier acuity","volume":"43","author":"Freeman RD","year":"1980","journal-title":"J Neurophysiol"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199207000-00007"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6989(95)00119-K"},{"key":"e_1_2_7_27_1","volume-title":"Measuring Vision and Vision Loss. 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