{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T03:08:57Z","timestamp":1774321737090,"version":"3.50.1"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2014,12,20]],"date-time":"2014-12-20T00:00:00Z","timestamp":1419033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      Previous reports showed increased flow velocities in retrobulbar vessels after glaucoma surgery in the first weeks. Colour Doppler imaging was performed to investigate the long\u2010term effects of trabeculectomy on retrobulbar haemodynamics in patients with primary open\u2013angle glaucoma (\n                      <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In a prospective study 30 patients (mean age 63.2\u00a0\u00b1\u00a015.4\u00a0years) with\n                      <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content>\n                      were included. Colour Doppler imaging was performed before 1\u20132\u00a0weeks, after 2\u00a0months, after 4\u20136\u00a0months, and up to 3\u00a0years after trabeculectomy to determine the peak systolic and end\u2013diastolic velocities in the ophthalmic artery, central retinal artery, and the short nasal and temporal posterior ciliary arteries.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean follow\u2010up was 416\u00a0\u00b1\u00a0246\u00a0days. In the first postsurgical period mean intraocular pressure (\n                      <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>\n                      ) decreased after trabeculectomy from 25\u00a0\u00b1\u00a06\u00a0mmHg to 9\u00a0\u00b1\u00a04\u00a0mm Hg (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001) and then increased in the further follow\u2010up to 13\u00a0\u00b1\u00a03\u00a0mmHg (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05) without any anti\u2013glaucomatous medication. Colour Doppler imaging revealed a significant increase of the end\u2013diastolic velocities of the central retinal artery at all postoperative visits compared to pre\u2013surgery (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.003) and of the end\u2013diastolic velocities in the temporal posterior ciliary arteries (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.003). The change of blood flow parameters that increased during follow\u2010up was significantly correlated to the change in ocular perfusion pressure and\n                      <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      End\u2013diastolic velocities of the central retinal artery and of the temporal posterior ciliary arteries increased after successful trabeculectomy and remained stable in a longer period \u2013 even if\n                      <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>\n                      rose significantly in the follow\u2010up.\n                    <\/jats:p>\n                  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