{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:58:21Z","timestamp":1780487901253,"version":"3.54.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Transient changes in corneal topography associated with soft and conventional or reverse geometry rigid contact lens wear have been well documented; however, only a few studies have examined the influence of scleral contact lens wear upon the cornea. Therefore, in this study, we examined the influence of modern miniscleral contact lenses, which land entirely on the sclera and overlying tissues, upon anterior corneal curvature and optics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Anterior corneal topography and elevation data were acquired using Scheimpflug imaging (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.pentacam.com\">www.pentacam.com<\/jats:ext-link>\n                      ) immediately prior to and following 8 h of miniscleral contact lens wear in 15 young healthy adults (mean age 22 \u00b1 3 years, eight East Asian, seven Caucasian) with normal corneae. Corneal diurnal variations were accounted for using data collected on a dedicated measurement day without contact lens wear. Corneal clearance was quantified using an optical coherence tomographer (\n                      <jats:styled-content style=\"fixed-case\">RS<\/jats:styled-content>\n                      \u20103000,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.nidek.com\">www.nidek.com<\/jats:ext-link>\n                      ) following lens insertion and after 8 h of lens wear.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Although corneal clearance was maintained throughout the 8\u2010h lens wear period, significant corneal flattening (up to 0.08 \u00b1 0.04 mm) was observed, primarily in the superior mid\u2010peripheral cornea, which resulted in a slight increase in against\u2010the\u2010rule corneal astigmatism (mean +0.02\/\u22120.15 \u00d7 94 for an 8 mm diameter). Higher order aberration terms of horizontal coma, vertical coma and spherical aberration all underwent significant changes for an 8 mm corneal diameter (\n                      <jats:italic>p<\/jats:italic>\n                      \u2264 0.01), which typically resulted in a decrease in\n                      <jats:styled-content style=\"fixed-case\">RMS<\/jats:styled-content>\n                      error values (mean change in total higher order\n                      <jats:styled-content style=\"fixed-case\">RMS<\/jats:styled-content>\n                      \u22120.035 \u00b1 0.046 \u03bcm for an 8 mm diameter). There was no association between the magnitude of change in central or mid\u2010peripheral corneal clearance during lens wear and the observed changes in corneal curvature (\n                      <jats:italic>p<\/jats:italic>\n                      &gt; 0.05). However, East Asian participants displayed a significantly greater reduction in corneal clearance (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.04) and greater superior\u2010nasal corneal flattening compared to Caucasians (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.048).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Miniscleral contact lenses that vault the cornea induce significant changes in anterior corneal surface topography and higher order aberrations following 8 h of lens wear. The region of greatest corneal flattening was observed in the superior\u2010nasal mid\u2010periphery, more so in East Asian participants. Practitioners should be aware that corneal measurements obtained following miniscleral lens removal may mask underlying corneal steepening.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.12270","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T00:37:19Z","timestamp":1450744639000},"page":"100-111","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Miniscleral lens wear influences corneal curvature and optics"],"prefix":"10.1007","volume":"36","author":[{"given":"Stephen J.","family":"Vincent","sequence":"first","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory School of Optometry and Vision Science Queensland University of Technology Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Alonso\u2010Caneiro","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory School 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