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With regard to vision research, prior to the advent of\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      , researchers relied on animal physiology and human post\u2010mortem work to assess the impact of eye disease on visual cortex and connecting structures. Using\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      , researchers can non\u2010invasively examine the effects of eye disease on the whole visual pathway, including the lateral geniculate nucleus, striate and extrastriate cortex. This review aims to summarise research using\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      to investigate structural, chemical and functional effects of eye diseases, including: macular degeneration, retinitis pigmentosa, glaucoma, albinism, and amblyopia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Findings<\/jats:title>\n                    <jats:p>\n                      Structural\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      has demonstrated significant abnormalities within both grey and white matter densities across both visual and non\u2010visual areas. Functional\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      studies have also provided extensive evidence of functional changes throughout the whole of the visual pathway following visual loss, particularly in amblyopia.\n                      <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\n                      spectroscopy techniques have also revealed several abnormalities in metabolite concentrations in both glaucoma and age\u2010related macular degeneration.\n                      <jats:styled-content style=\"fixed-case\">GABA<\/jats:styled-content>\n                      \u2010edited\n                      <jats:styled-content style=\"fixed-case\">MR<\/jats:styled-content>\n                      spectroscopy on the other hand has identified possible evidence of plasticity within visual cortex.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>\n                      Collectively, using\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      to investigate the effects on the visual pathway following disease and dysfunction has revealed a rich pattern of results allowing for better characterisation of disease. In the future\n                      <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                      will likely play an important role in assessing the impact of eye disease on the visual pathway and how it progresses over time.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.12293","type":"journal-article","created":{"date-parts":[[2016,4,26]],"date-time":"2016-04-26T16:06:23Z","timestamp":1461686783000},"page":"240-265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Using magnetic resonance imaging to assess visual deficits: a review"],"prefix":"10.1007","volume":"36","author":[{"given":"Holly D. 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