{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T18:28:09Z","timestamp":1782584889744,"version":"3.54.5"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T00:00:00Z","timestamp":1616716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To quantify the effect of a single scleral lens design on visual acuity and ocular higher\u2010order aberrations in eyes with post\u2013LASIK ectasia, keratoconus and pellucid marginal degeneration (PMD) that could not achieve satisfactory vision with spectacles or soft contact lenses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Forty\u2010six eyes of 28 participants fitted with diagnostic scleral lenses (KeraCare) were analysed, including 19, 15 and 12 eyes with post\u2010LASIK ectasia, keratoconus and PMD, respectively. Corrected distance visual acuity (CDVA) and ocular aberrations were measured prior to lens wear and during lens wear after 60\u00a0min of settling. An i\u2013Trace aberrometer was used to determine aberrations over a 4.5\u00a0mm diameter pupil.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Before lens wear, the median (95% confidence interval) values across all groups were: CDVA 0.30 (0.30, 0.40) logMAR, spherical equivalent refraction \u20132.75 (\u20135.25, \u20132.12) D, cylindrical refraction 3.75 (2.50, 5.00) D, higher\u2013order\u2013root\u2013mean\u2013square error (HO\u2010RMS) 0.90 (0.64, 1.03) \u03bcm and vertical coma co\u2010efficient C(3,\u20131) \u20130.32 (\u20130.42, \u20130.12) \u03bcm. RMS coma of 0.52 (0.40, 0.74) \u03bcm was higher for the keratoconus group than for the other groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). During lens wear, values improved considerably across all groups: CDVA 0.0 (0.0, 0.00) logMAR, spherical equivalent refraction \u20130.50 (\u20130.75, +0.50) D, cylindrical refraction 0.50 (0.00, 0.50) D, HO\u2010RMS 0.32 (0.26, 0.42) \u03bcm and C(3,\u20131) +0.12 (+0.02, +0.19) \u03bcm (all\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001 compared to pre\u2010lens wear). While reduced significantly, RMS coma remained higher in the keratoconus group at 0.35 (0.31, 0.52) \u03bcm than in the post\u2013LASIK ectasia and PMD groups at 0.17 (0.12, 0.21) \u03bcm and 0.07 (0.02, 0.46) \u03bcm, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The KeraCare scleral contact lens reduced ocular aberrations and improved visual acuity in patients with post\u2013LASIK ectasia, keratoconus and PMD. The sign of vertical coma changed in keratoconus and PMD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.12802","type":"journal-article","created":{"date-parts":[[2021,3,26]],"date-time":"2021-03-26T09:35:56Z","timestamp":1616751356000},"page":"664-672","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["The effect of scleral lenses on vision, refraction and aberrations in post\u2010LASIK ectasia, keratoconus and pellucid marginal degeneration"],"prefix":"10.1007","volume":"41","author":[{"given":"Mukesh","family":"Kumar","sequence":"first","affiliation":[{"name":"Narayana Nethralaya Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Shetty","sequence":"additional","affiliation":[{"name":"Narayana Nethralaya Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaitheeswaran 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