{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:41:19Z","timestamp":1783600879356,"version":"3.55.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T00:00:00Z","timestamp":1661385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011779","name":"Brien Holden Vision Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine the efficacy of two myopia control contact lenses (CL) compared with a single\u2010vision (SV) CL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ninety\u2010five Chinese children with myopia, aged 7\u201313\u2009years in a 1\u2010year prospective, randomised, contralateral, cross\u2010over clinical trial with 3 groups; bilateral SVCL (Group I); randomised, contralateral wear of an extended depth of focus (EDOF) CL and SVCL (Group II) and MiSight\u00ae CL and SVCL (Group III). In Groups II and III, CL were crossed over at the 6\u2010month point (Stage 1) and worn for a further 6\u00a0months (Stage 2). Group I wore SVCL during both stages. At baseline and the end of each stage, cycloplegic spherical equivalent refractive error (SE) and axial length (AL) were measured. Six\u2010monthly \u0394SE\/\u0394AL across groups was analysed using a linear mixed model (CL type, stage, eye and eye* stage included as factors). Intra\u2010group paired differences between eyes were determined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In Group I, mean (SD) \u0394SE\/\u0394AL with SVCL was \u22120.41 (0.28)\u00a0D\/0.13 (0.09)\u00a0mm and \u22120.25 (0.27)\u00a0D\/0.16 (0.09)\u00a0mm for stages 1 and 2, with a mean paired difference between eyes of 0.01\u2009D\/0.01\u2009mm and 0.05\u2009D\/\u22120.01\u2009mm, respectively. \u0394SE\/\u0394AL with SVCL was similar across Groups I to III (Stage 1:\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.89\/0.44, Stage 2:\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.70\/ 0.64). In Groups II and III, \u0394SE\/\u0394AL was lower with the EDOF and MiSight\u00ae CL than the contralateral SVCL in 68% to 94% of participants, and adjusted 6\u2010month \u0394SE\/\u0394AL with EDOF was similar to MiSight\u00ae (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.49\/0.56 for \u0394SE\/\u0394AL, respectively). Discontinuations across the three groups were high, but not different between the groups (33.3%, 48.4% and 50% for Groups I to III, respectively [\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.19]) and most discontinuations occurred immediately after baseline.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Extended depth of focus and MiSight\u00ae CL demonstrated similar efficacy in slowing myopia. When switched from a myopia control CL to SVCL, myopia progression was similar to that observed with age\u2010matched wearers in SVCL and not suggestive of rebound.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13042","type":"journal-article","created":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T12:00:25Z","timestamp":1661428825000},"page":"1253-1263","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Efficacy of contact lenses for myopia control: Insights from a randomised, contralateral study design"],"prefix":"10.1007","volume":"42","author":[{"given":"Rebecca","family":"Weng","sequence":"first","affiliation":[{"name":"Brien Holden Vision Institute  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3829-7415","authenticated-orcid":false,"given":"Weizhong","family":"Lan","sequence":"additional","affiliation":[{"name":"Aier Institute of Optometry and Vision Science  Changsha China"},{"name":"Aier School of Ophthalmology Central South University  Changsha China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Bakaraju","sequence":"additional","affiliation":[{"name":"Brien Holden Vision Institute  Sydney New South Wales Australia"},{"name":"School of Optometry and Vision Science University of New South Wales  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Conrad","sequence":"additional","affiliation":[{"name":"Brien Holden Vision Institute  Sydney New South Wales Australia"},{"name":"School of Optometry and Vision Science University of New South Wales  Sydney New South Wales 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