{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T05:38:46Z","timestamp":1782365926538,"version":"3.54.5"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003132","name":"Agentschap voor Innovatie door Wetenschap en Technologie","doi-asserted-by":"publisher","award":["IWT\/110684"],"award-info":[{"award-number":["IWT\/110684"]}],"id":[{"id":"10.13039\/501100003132","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["FWO\u2010TBM T000416N"],"award-info":[{"award-number":["FWO\u2010TBM T000416N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["R01 EY008520"],"award-info":[{"award-number":["R01 EY008520"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["R01 EY019105"],"award-info":[{"award-number":["R01 EY019105"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To investigate whether the movement of a rigid sphero\u2010cylindrical contact lens has a greater impact on the visual image quality in highly aberrated eyes than in normal eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      For 20 normal and 20 keratoconic SyntEyes, a previously determined best sphero\u2010cylindrical rigid lens was permitted to shift by up to \u00b11\u2009mm from the line of sight and rotate up to \u00b115\u00b0. Each of the 52,111 lens locations sampled was ray\u2010traced to determine the influence on the wavefront aberration. In turn, the logarithm of visual Strehl ratio (log\n                      <jats:sub>10<\/jats:sub>\n                      [VSX]) was calculated for each aberration structure and was used to estimate the associated changes in logMAR visual acuity. Finally, contour surfaces of two\u2010letter change in visual acuity were plotted in three\u2010dimensional misalignment space, consisting of decentrations in the\n                      <jats:italic>x<\/jats:italic>\n                      and\n                      <jats:italic>y<\/jats:italic>\n                      directions and rotation, and volumes within these surfaces were calculated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The variations in image quality within the misalignment space were unique to each eye. A two\u2010letter loss was generally reached with smaller misalignments in keratoconic eyes (10.5\u00a0\u00b1\u20094.7\u00b0 of rotation or 0.27\u2009\u00b1\u20090.13\u2009mm of shift) than in normal eyes (13.4\u00a0\u00b1\u20091.8\u00b0 and 0.39\u2009\u00b1\u20090.15\u2009mm, respectively) due to larger cylindrical errors. For keratoconic eyes, on average, 14.4\u00a0\u00b1\u200914.9% of misalignment space saw VSX values above the lower normal VSX threshold, well below the values of normal eyes of 48.5\u00a0\u00b1\u200918.5%. In some eyes, a specific combination of lens shift and lens rotation away from the line of sight leads to a simulated improvement in visual image quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Variations in visual image quality due to the misalignment of rigid sphero\u2010cylindrical contact lens corrections are larger for keratoconic eyes than for normal eyes. In some cases, a specific misalignment may improve visual image quality, which could be considered in the design of the next generation of rigid contact lenses.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13045","type":"journal-article","created":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T06:15:21Z","timestamp":1663308921000},"page":"1204-1213","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Influence of rigid lens decentration and rotation on visual image quality in normal and keratoconic eyes"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8124-8646","authenticated-orcid":false,"given":"Jos J.","family":"Rozema","sequence":"first","affiliation":[{"name":"Visual Optics Lab Antwerp (VOLANTIS), Faculty of Medicine and Health Sciences Antwerp University  Wilrijk Belgium"},{"name":"Department of Ophthalmology Antwerp University Hospital  Edegem 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