{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:09:09Z","timestamp":1791248949472,"version":"4.1.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,3,15]],"date-time":"2023-03-15T00:00:00Z","timestamp":1678838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002911","name":"Universidad Complutense de Madrid","doi-asserted-by":"publisher","award":["(grant number CT63\/19\u2010CT64\/19)."],"award-info":[{"award-number":["(grant number CT63\/19\u2010CT64\/19)."]}],"id":[{"id":"10.13039\/501100002911","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>To evaluate the backscattered light, objective scatter index (OSI) and retinal straylight in patients with moderate keratoconus and healthy control subjects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective observational study was developed with 33 patients in the moderate\u2010keratoconus group (KC) and 34 in the non\u2010keratoconus group (NKC). Corneal densitometry was obtained using Scheimpflug corneal tomography and measurements were expressed in grayscale units (GSU) over four zones within a 12.00\u2009mm diameter around the corneal apex. A straylight meter was used to determine the amount of intraocular straylight under scotopic conditions, and the straylight parameter (LOG(s)) and test duration were recorded. The Optical Quality Analysis System based on the double\u2010pass technique determined the OSI value.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Significant differences were observed between the KC and NKC groups for corneal densitometry (except in the 6\u201310\u2009mm zone), OSI and retinal straylight. A moderate and significant correlation was found between OSI and retinal straylight LOG(s) (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.52,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.002). Weaker and non\u2010significant correlations were found between corneal densitometry and the other parameters analysed (i.e., OSI, retinal straylight LOG(s) and retinal straylight times).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Backscattered light, retinal straylight and the OSI show clear differences between healthy eyes and those with moderate KC. The changes present in the stages of KC evaluated in the current study (stages II and III according to the Amsler\u2013Krumeich classification) might alter the scattering of the light entering the eye.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13126","type":"journal-article","created":{"date-parts":[[2023,3,15]],"date-time":"2023-03-15T09:39:46Z","timestamp":1678873186000},"page":"752-759","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Forward\u2010scattered and backward\u2010scattered light in moderate keratoconus"],"prefix":"10.1007","volume":"43","author":[{"given":"Celia","family":"Villanueva","sequence":"first","affiliation":[{"name":"Optometry and Vision Department, Faculty of Optics and Optometry Universidad Complutense de Madrid  Madrid Spain"},{"name":"Ophthalmology Department Hospital Cl\u00ednico San Carlos  Madrid 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