{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T14:30:13Z","timestamp":1767796213880,"version":"3.49.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>While optical coherence tomography (OCT) measurements of the lower tear meniscus height (LTMH) have been reported in adults, here we obtained LTMH measurements through Fourier Domain OCT in healthy children and compared these with values obtained in healthy adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were children 7\u201317\u2009years of age and a control group of adults 20\u201340\u2009years of age. Inclusion criteria were no abnormal eye conditions or the use of contact lenses. Candidates who fulfilled the TFOS DEWS II criteria for dry eye disease (DED) were excluded. All subjects underwent LTMH measurement (OCT Spectralis) and tests for non\u2010invasive tear break\u2010up time and ocular surface staining. Participants also completed the ocular surface disease index questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 86 children and 27 adults were included. Mean LTMH values in the children and adult groups were 217.40\u2009\u00b1\u200971.40\u2009\u03bcm and 225.0\u2009\u00b1\u200954.86\u2009\u03bcm, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.53. However, 59.3% of the children had an LTMH \u2264210\u2009\u03bcm suggestive of DED, compared with only 33.3% of adults (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02). For the children, no significant differences in LTMH were observed with sex or for those more or less than 12\u2009years of age.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Optical coherence tomography\u2010derived LTMH measurements were obtained in healthy children. While values were similar in children and adults, a greater proportion of children had an LTMH compatible with a diagnosis of DED. More studies in different paediatric populations are required to establish a complete set of normative LTMH measurements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13157","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T01:23:41Z","timestamp":1682645021000},"page":"1059-1064","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lower tear meniscus height measured by optical coherence tomography in children"],"prefix":"10.1007","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5238-315X","authenticated-orcid":false,"given":"Beatriz","family":"Martin\u2010Garc\u00eda","sequence":"first","affiliation":[{"name":"Optometry and Vision Department, Faculty of Optics and Optometry Universidad Complutense de Madrid  Madrid 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