{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T14:01:38Z","timestamp":1778076098546,"version":"3.51.4"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T00:00:00Z","timestamp":1683763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>One clinical approach to address poor front surface wettability during scleral lens wear is the use of a \u201creverse piggyback\u201d system (a soft contact lens applied to the anterior surface of a scleral lens). The aim of this study was to compare the magnitude of corneal oedema induced following short\u2010term reverse piggyback scleral lens wear and standard scleral lens wear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Ten young (mean age 22\u2009\u00b1\u20096\u2009years) healthy participants with normal corneas were recruited. On separate days, central corneal thickness and fluid reservoir thickness were measured using optical coherence tomography before and after 90\u2009min of standard scleral lens wear (Kerectasia Alignment Tangent Torus diagnostic lenses, hexafocon A, Dk 100\u2009\u00d7\u200910\n                      <jats:sup>\u221211<\/jats:sup>\n                      (cm\n                      <jats:sup>2<\/jats:sup>\n                      \/s)(ml O\n                      <jats:sub>2<\/jats:sub>\n                      \/ml \u00d7 mmHg), Capricornia Contact Lenses,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/capcl.com.au\">capcl.com.au<\/jats:ext-link>\n                      ) and reverse piggyback scleral lens wear (the same scleral lens with a Dailies Total 1\u00ae, delefilcon A, Dk 140\u2009\u00d7\u200910\n                      <jats:sup>\u221211<\/jats:sup>\n                      (cm\n                      <jats:sup>2<\/jats:sup>\n                      \/s)(ml O\n                      <jats:sub>2<\/jats:sub>\n                      \/ml \u00d7 mmHg), Alcon,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/alcon.com\">alcon.com<\/jats:ext-link>\n                      , applied to the anterior scleral lens surface).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After correcting for small variations in the initial central fluid reservoir thickness, central corneal oedema was similar between the reverse piggyback (2.32\u2009\u00b1\u20091.15%) and standard scleral lens conditions (2.02\u2009\u00b1\u20090.76%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.45).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Following 90\u2009min of lens wear, the highly oxygen\u2010permeable reverse piggyback system did not induce a clinically or statistically greater magnitude of central corneal oedema compared with standard scleral lens wear in young adults with healthy corneas. This approach may be suitable to address poor front surface scleral lens wettability or to correct residual refractive error during diagnostic scleral lens fitting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13161","type":"journal-article","created":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:13:12Z","timestamp":1683850392000},"page":"1065-1069","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Corneal oedema during reverse piggyback scleral lens wear"],"prefix":"10.1007","volume":"43","author":[{"given":"Vyasa H.","family":"Bliss","sequence":"first","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan","family":"Branjerdporn","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng Jia","family":"Ooi","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li Mei","family":"Teo","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jervis","family":"Tu","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Yeh","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5226-5498","authenticated-orcid":false,"given":"Michael J.","family":"Collins","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5998-1320","authenticated-orcid":false,"given":"Stephen J.","family":"Vincent","sequence":"additional","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Centre for Vision and Eye Research Queensland University of Technology  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,5,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199301000-00010"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0b013e31815b7d91"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2019.12.007"},{"key":"e_1_2_8_5_1","unstructured":"MelchioneC KadingD.Soft contact lens scleral piggyback to reduce fogging (Poster). 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Available from:http:\/\/www.clspectrum.com\/supplements\/2013\/june\u20102013\/the\u2010world\u2010x0027;s\u2010first\u2010and\u2010only\u2010water\u2010gradient\u2010c\/font\u2010color\u2010000000\u2010special\u2010edition\u20102013\u2010font\u2010(11)"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000514"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2019.12.008"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20151207-03"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2018.03.001"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.12814"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000852"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.13005"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-197710000-00003"}],"container-title":["Ophthalmic and Physiological Optics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/opo.13161","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T11:26:54Z","timestamp":1767785214000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/opo.13161"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,11]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/opo.13161"],"URL":"https:\/\/doi.org\/10.1111\/opo.13161","archive":["Portico"],"relation":{},"ISSN":["0275-5408","1475-1313"],"issn-type":[{"value":"0275-5408","type":"print"},{"value":"1475-1313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,11]]},"assertion":[{"value":"2023-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}