{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:43:56Z","timestamp":1785192236533,"version":"3.55.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T00:00:00Z","timestamp":1700179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To assess the reliability and agreement of non\u2010invasive break\u2010up time (NIBUT) in symptomatic and asymptomatic contact lens (CL) wearers using automatic objective and conventional subjective techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective cross\u2010sectional study, soft CL wearers, classified into symptomatic and asymptomatic based on the Contact Lens Dry Eye Questionnaire\u20108, underwent NIBUT assessment with the CL in\u00a0situ. The CA\u2010800 Corneal Analyzer and the EasyTear\u00ae VIEW+ Tearscope were used for objective and subjective evaluation, respectively. The within\u2010subject repeatability and intraclass correlation coefficient (ICC) were calculated. The agreement between the devices was compared using the Bland\u2013Altman method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 141 CL wearers (51 male and 90 female) with a mean age of 33.6 (SD\u2009=\u200912.2) years were included. The repeatability and ICC values obtained with the CA\u2010800 device when measuring NIBUT were 5.4\u2009s and 58.6% across the whole sample, 4.2\u2009s and 48.8% for the asymptomatic group and 7.1\u2009s and 68.4% for the symptomatic group. When using the subjective method (EasyTear\u00ae), the respective repeatability and ICC values were 7.3\u2009s and 32.7% for the whole sample, 6.5\u2009s and 30.4% for the asymptomatic group and 8.6\u2009s and 35.9% for the symptomatic group. The CA\u2010800 device provided significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) shorter NIBUT values compared with EasyTear\u00ae for the whole sample (3.3 [2.9] vs. 8.1 [3.4] s), the asymptomatic (3.3 [3.0] vs. 7.7 [3.6] s) and the symptomatic (3.8 [2.9] vs. 8.6 [3.0] s) groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Objective (CA\u2010800) NIBUT assessment provides more reliable measurements than the conventional subjective technique using the EasyTear\u00ae device. However, CL practitioners should also be aware that the objective method indicates shorter NIBUT values. Symptomatic CL wearers may also need a higher number of NIBUT measurements to obtain reliable estimations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13243","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T04:01:57Z","timestamp":1700193717000},"page":"124-130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Reliability and agreement of subjective and objective non\u2010invasive break\u2010up time measurements in contact lens wearers"],"prefix":"10.1007","volume":"44","author":[{"given":"Laura","family":"Valencia\u2010Nieto","sequence":"first","affiliation":[{"name":"Instituto de Oftalmobiolog\u00eda Aplicada (IOBA) Universidad de Valladolid  Valladolid Spain"},{"name":"Departamento de F\u00edsica Te\u00f3rica, At\u00f3mica y \u00d3ptica, Facultad de Ciencias Universidad de Valladolid  Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6017-8618","authenticated-orcid":false,"given":"Alberto","family":"L\u00f3pez\u2010de\u00a0la\u00a0Rosa","sequence":"additional","affiliation":[{"name":"Instituto de Oftalmobiolog\u00eda Aplicada (IOBA) Universidad de Valladolid  Valladolid Spain"},{"name":"Departamento de F\u00edsica Te\u00f3rica, At\u00f3mica y \u00d3ptica, Facultad de Ciencias Universidad de Valladolid  Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3673-0585","authenticated-orcid":false,"given":"Mar\u00eda J.","family":"Gonz\u00e1lez\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Instituto de Oftalmobiolog\u00eda Aplicada (IOBA) Universidad de Valladolid  Valladolid Spain"},{"name":"Departamento de F\u00edsica Te\u00f3rica, At\u00f3mica y \u00d3ptica, Facultad de Ciencias Universidad de Valladolid  Valladolid Spain"},{"name":"Biomedical Research Networking Centre in Bioengineering Biomaterials and Nanomedicine (CIBER\u2010BBN)  Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9429-1571","authenticated-orcid":false,"given":"Alberto","family":"L\u00f3pez\u2010Miguel","sequence":"additional","affiliation":[{"name":"Instituto de Oftalmobiolog\u00eda Aplicada (IOBA) Universidad de Valladolid  Valladolid Spain"},{"name":"Departamento de Cirug\u00eda, Oftalmolog\u00eda, Otorrinolaringolog\u00eda y Fisioterapia, Facultad de Medicina Universidad de Valladolid  Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,11,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.76.3.157"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-312333"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-0685"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000727"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3181b598cd"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273948.2019.1668024"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/opo.12338"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2018.1437454"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2020.02.018"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2012.04.002"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3182714425"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2017.1393092"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/app12094589"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2020.08.006"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S110180"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-13074"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e318269c90d"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1313.2011.00851.x"},{"key":"e_1_2_10_20_1","first-page":"268","volume-title":"An introduction to medical statistics","author":"Bland M","year":"2000"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.313.7059.744"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.313.7048.41"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/096228029900800204"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199910000-00021"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1986.tb06904.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0b013e3181dae228"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0938.1999.tb06639.x"},{"key":"e_1_2_10_28_1","first-page":"28","article-title":"International contact lens prescribing in 2022","volume":"38","author":"Morgan PB","year":"2023","journal-title":"Contact Lens Spectrum"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000927"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000920"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/8013621"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.02.012"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000648"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-17772"},{"key":"e_1_2_10_35_1","first-page":"21","article-title":"Tear film examination of the contact lens patient","volume":"206","author":"Guillon J","year":"1993","journal-title":"Optician"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-198303000-00004"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtos.2017.05.001"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199501000-00004"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-018-3986-9"}],"updated-by":[{"DOI":"10.1111\/opo.13470","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T00:00:00Z","timestamp":1742169600000}}],"container-title":["Ophthalmic and Physiological Optics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/opo.13243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T11:23:57Z","timestamp":1767785037000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/opo.13243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,17]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1111\/opo.13243"],"URL":"https:\/\/doi.org\/10.1111\/opo.13243","archive":["Portico"],"relation":{},"ISSN":["0275-5408","1475-1313"],"issn-type":[{"value":"0275-5408","type":"print"},{"value":"1475-1313","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,17]]},"assertion":[{"value":"2023-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}