{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T14:19:09Z","timestamp":1767795549249,"version":"3.49.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171057"],"award-info":[{"award-number":["82171057"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to profile ocular biometry parameters and predictors of spherical equivalent refraction (SER) among children with moderate to high hyperopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Individuals &lt;18\u2009years of age with moderate to high hyperopia were enrolled from November 2015 to November 2021. Participants underwent a series of comprehensive ocular examinations, and were classified as having low hyperopia, that is, SER +0.5 to &lt; +2.0\u2009D or moderate to high hyperopia, that is, SER \u2265 +2.0\u2009D.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 459 and 230 eyes with moderate to high hyperopia and low hyperopia, respectively, were included. Moderate to high hyperopic eyes had a shorter axial length, stronger lens power (24.78\u2009\u00b1\u20095.47 D vs. 18.74\u2009\u00b1\u20091.63\u2009D,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and weaker corneal power (42.82\u2009\u00b1\u20091.75\u2009D vs. 43.31\u2009\u00b1\u20091.55\u2009D,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) than low hyperopic eyes. When comparing values before and after 5\u2009years of age, both lens power and axial length differed significantly in the moderate to high hyperopia group, whereas in the low hyperopia group, they only differed significantly after 9\u2009years of age. Lens power was negatively associated with AL in eyes with axial lengths between 20 and 22\u2009mm. A multiple linear regression model which included axial length (standardised\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.80,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), corneal power (standardised\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.47,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and lens power (standardised\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.23,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) explained 81.2% of the variance in SER.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Differences in lens power and axial length in moderate to high hyperopic eyes became significantly smaller after 5\u2009years of age, at least 4\u2009years earlier than for the low hyperopia. Lens power could offset the axial elongation in participants with axial lengths between 20 and 22\u2009mm, suggesting that children with moderate to high hyperopia might have different ocular growth patterns. Axial length, corneal power and lens power were the main predictors of SER in moderate to high hyperopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13266","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T23:12:25Z","timestamp":1704237145000},"page":"292-300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lens power, cornea power and association with refractive error in children with moderate to high hyperopia"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0275-0781","authenticated-orcid":false,"given":"Zhirong","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Centre for Ocular Diseases Sun Yat\u2010Sen University  Guangzhou China"},{"name":"Foshan Woman and Children Hospital  Foshan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0602-288X","authenticated-orcid":false,"given":"Ruiyu","family":"Luo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Centre for Ocular Diseases Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehong","family":"Zhuo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Centre for Ocular Diseases Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daming","family":"Deng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Centre for Ocular Diseases Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,1,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.09.036"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000001837"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-1040"},{"key":"e_1_2_9_5_1","first-page":"120","article-title":"Optical and structural development of the crystalline lens in childhood","volume":"39","author":"Mutti DO","year":"1998","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.17-22639"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2020.07.007"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-9637"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.18-26435"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.05.030"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1313.1988.tb01082.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.08.050"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20090505-05"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.922303"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2017.04.010"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3181b2f903"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.992587"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5441"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713680590959295"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010020\u201000231\u20104"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-18047"},{"key":"e_1_2_9_22_1","doi-asserted-by":"crossref","unstructured":"IribarrenR.Crystalline lens and refractive development. 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