{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T06:05:25Z","timestamp":1776319525730,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T00:00:00Z","timestamp":1721433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001793","name":"Queensland University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001793","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To quantify the impact of varying central fluid reservoir depth, lens thickness\/mass and the addition of a peripheral fenestration upon scleral lens centration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Ten young, healthy adults participated in a series of repeated\u2010measures experiments involving short\u2010term (90\u2009min) open eye scleral lens wear. Scleral lens parameters (material, back optic zone radius, diameter, back vertex power and landing zone) were controlled across all experiments, and the central fluid reservoir depth (ranging from 144 to 726\u2009\u03bcm), lens thickness (ranging from 150 to 1200\u2009\u03bcm), lens mass (101\u2013241\u2009mg)\u00a0and lens design (with or without a single 0.3\u2009mm peripheral fenestration) were altered systematically. Scleral lens decentration was quantified using over\u2010topography maps.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      On average, scleral lens centration varied by &lt;0.10\u2009mm over 90\u2009min of wear. Medium and high initial fluid reservoir conditions resulted in 0.17\u2009mm more temporal and 0.55\u2009mm more inferior lens decentration, compared to the low fluid reservoir depth (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Changes in lens thickness or the addition of a peripheral fenestration did not cause clinically significant changes in centration (&lt;0.10\u2009mm on average) when controlling for fluid reservoir depth. Central fluid reservoir depth was the best predictor of horizontal and vertical lens decentration, explaining 62\u201373% of the observed variation, compared to 40\u201344% for lens thickness and mass.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Scleral lens decentration remained relatively stable over 90\u2009min of lens wear. A greater initial central fluid reservoir depth resulted in significantly more lens decentration, particularly inferiorly. Large variations in lens thickness, mass\u00a0or the addition of a single peripheral fenestration did not substantially affect lens centration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13367","type":"journal-article","created":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T01:29:10Z","timestamp":1721525350000},"page":"1530-1538","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The effect of lens and fitting characteristics upon scleral lens centration"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4413-5196","authenticated-orcid":false,"given":"Damien","family":"Fisher","sequence":"first","affiliation":[{"name":"Contact Lens and Visual Optics Laboratory Queensland University of Technology, Optometry and Vision Science, Centre for Vision and Eye Research  Brisbane Queensland 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