{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:34:28Z","timestamp":1780065268856,"version":"3.54.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T00:00:00Z","timestamp":1724371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012909","name":"College of Optometrists","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012909","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmic Physiologic Optic"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To determine if supplementing standard clinical assessments with Optical Coherence Tomography (OCT) imaging of the crystalline lens improves the accuracy and precision of lens opacity assessment and associated clinical management decisions by optometrists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Fifty optometrists registered in the UK or \u00c9ire undertook a clinical vignette study where participants graded lens opacities and made associated clinical management decisions based on the image(s)\/information displayed. Three forms of vignettes were presented: (1) Slit\u2010lamp (SL) images of the lens, (2) SL and OCT images and (3) SL, OCT and visual function measures. Vignettes were constructed using anonymised data from 50 patients with varying cataract severity, each vignette being presented twice in a randomised order (total vignette presentations\u2009=\u2009300). The accuracy of opacity and management decisions were evaluated using descriptive statistics and non\u2010parametric Bland\u2013Altman analysis where assessments from experienced clinicians were the reference. The precision of assessments was examined for each vignette form using non\u2010parametric Bland\u2013Altman analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950) participants completed the study, with 36 working in primary eyecare (primary eyecare) settings and 14 in hospital eyecare services (HES). Agreement was highest where vignettes contained all clinical data (i.e., SL, OCT and visual function data\u2014grading: 51.0%, management: 50.5%), and systematically reduced with decreasing vignette content (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A larger number of vignettes containing imaging and visual function measures exhibited below reference (i.e., less conservative) grading compared with vignettes containing imaging data alone (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). HES\u2010based optometrists were more likely to grade lens opacities lower than clinicians working in primary eyecare (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Good measurement precision was evident for all vignettes, with a mean bias close to zero and limits of agreement below one grading step for all conditions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The addition of anterior segment OCT to SL images improved the accuracy of lens opacity grading. Structural assessment alone yielded more conservative decision making, which reversed once visual functional data was available.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/opo.13383","type":"journal-article","created":{"date-parts":[[2024,8,24]],"date-time":"2024-08-24T02:40:58Z","timestamp":1724467258000},"page":"1539-1551","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Investigating the impact of\n                    <scp>OCT<\/scp>\n                    imaging of the crystalline lens on the accuracy and precision of cataract assessment"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2178-8050","authenticated-orcid":false,"given":"Niamh","family":"Burke","sequence":"first","affiliation":[{"name":"Centre for Optometry and Vision Science, Biomedical Sciences Research Institute Ulster University  Coleraine UK"},{"name":"National Institute for Health &amp; Care Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5166-0592","authenticated-orcid":false,"given":"P\u00e1draig J.","family":"Mulholland","sequence":"additional","affiliation":[{"name":"Centre for Optometry and Vision Science, Biomedical Sciences Research Institute Ulster University  Coleraine UK"},{"name":"National Institute for Health &amp; Care Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9239-745X","authenticated-orcid":false,"given":"Pearse A.","family":"Keane","sequence":"additional","affiliation":[{"name":"National Institute for Health &amp; Care Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5242-8066","authenticated-orcid":false,"given":"Julie\u2010Anne","family":"Little","sequence":"additional","affiliation":[{"name":"Centre for Optometry and Vision Science, Biomedical Sciences Research Institute Ulster University  Coleraine UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,23]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"1506","article-title":"Age\u2010related changes in the kinetics of human lenses: prevention of the cataract","volume":"9","author":"Pescosolido N","year":"2016","journal-title":"Int J Ophthalmol"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3283414284"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(17)30393-5"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-304033"},{"key":"e_1_2_12_6_1","unstructured":"The Royal College of Ophthalmologists. 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